Metacure Limited

Enopace Biomedical Ltd.

Rainbow Medical Ltd.

Offer Glasberg

Amir Dagan

Gal Ariav

Nitai Hanani

Yotam Reisner

Yossi Gross

Tami Harel

Benny Rousso

Shai Policker

David Prutchi

Yuval Mika

Oded Meiri

Ophir Bitton

Lena Milman

Tamir S Levi

Nissim Darvish

Bella Felsen

Yuval Elovici

Elazar Sonnenschein

Amir Govrin

Minelu Sonnenschein

Walid Haddad

Paul Richard Spehr

Aharon Grossman

Moshe Elazar

Igor Gindin

Vadim Bernshtein

Nir Armony

Radwan Khawaled

Apparatus and methods are described including a mechanical support element that is placed inside a first vein of a subject. At least one electrode disposed on the mechanical support element is placed inside the first vein, in a vicinity of a site upstream of a bifurcation with a second vein of the subject. A control unit enhances downstream blood flow from the first vein by driving the at least one electrode to divert blood downstream into the second vein by constricting the first vein at the upstream site, by driving the at least one electrode to apply a current to the vicinity of the site. The mechanical support element prevents the first vein from collapsing by providing mechanical support to the vein. Other embodiments are also described.

Enhancing perfusion by contraction

Apparatus and methods are provided for use with a blood vessel of a subject, including a stent () configured to be placed in the blood vessel. The stent includes at least first (), second (), and third () strut portions disposed along the stent. The first and second strut portions are coupled to one another at a first junction (A) that facilitates bending of the first and second strut portions with respect to one another. The second and third strut portions are coupled to one another at a second junction (B) that facilitates bending of the second and third strut portions with respect to one another. At least one electrode () is disposed on at least an outer surface of the stent. Other applications are also described.

Wireless endovascular stent-based electrodes

Apparatus is provided, including (1) an external device, configured for placement outside of a body of a subject and to sense a factor of the subject, and to generate a signal in response to the sensed factor, and (2) an implant, which comprises a wireless receiver for receiving the signal, and at least one electrode, the implant configured to drive the electrode to apply current to an aortic and/or vagal site of the subject in response to the signal.

Detector-based arterial stimulation

A method of glucose level control, comprising providing at least one electrode adapted to apply an electric field to a pancreas; and applying an electric field to the pancreas using the above-mentioned at least one electrode such that blood glucose levels are significantly reduced and blood insulin levels are not significantly increased.

Blood glucose level control

Apparatus and methods are provided for use with a heart of a subject, including a set of one or more electrodes. A control unit paces the heart by driving a first electric current via the electrode set into tissue of the subject, in accordance with a first set of parameters. The control unit stimulates nitric oxide production by a portion of the heart by driving a second electric current via the electrode set into the portion of the heart, in accordance with a second set of parameters. Other embodiments are also described.

Pacemaker with no production

Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of congestive heart failure, diastolic heart failure, acute myocardial infarction, and hypertension. In response to the identifying, an electrode is placed on the subject's aorta at an aortic site that is between a bifurcation of the aorta with the subject's left subclavian artery and a bifurcation of the aorta with the subject's fifth intercostal artery. The subject is treated by electrically stimulating the aortic site by driving a current into the aortic site, via the electrode. Other applications are also described.

Acute myocardial infarction treatment by electrical stimulation of the thoracic aorta

Apparatus and methods are provided, including an electrode that is placed in contact with an artery of a subject. A control unit drives the electrode to perform a function with respect to the artery, the function selected from the group consisting of: driving a current into the artery, and sensing an electrical parameter of the artery. A transmitter is placed in a vein of the subject that is in a vicinity of the artery, the transmitter being wiredly connected to the control unit. The control unit is configured to drive the electrode by wirelessly transmitting a signal via the transmitter. Other embodiments are also described.

Thoracic aorta and vagus nerve stimulation

Apparatus () is provided including an electrode () and an implantation tool () configured to be passed into an abdominal cavity of a patient, and to insert the electrode into a gastric wall of the patient, generally in parallel to the gastric wall. Other embodiments are also described.

Electrode assemblies, tools, and methods for gastric wall implantation

A method is provided, including physically contacting a gastric implantation site of a stomach via a transluminal approach, physically contacting the site via a transabdominal approach, stabilizing the site, and implanting an electrode at the site based on the physical contact provided by the transluminal and transabdominal approach. Other embodiments are also described.

GI lead implantation

Apparatus is provided, including a control unit (), adapted to be implanted within a patient (), and a corkscrew-shaped electrode mount (), adapted to be implanted in a wall of a stomach of the patient. The corkscrew-shaped electrode mount includes first () and second () electrodes, at respective sites of the electrode mount, and a controller (), wirelessly coupled to the control unit. Other embodiments are also described.

Wireless leads for gastrointestinal tract applications

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Zichron Yaakov, Israel

Offer Glasberg