Cornell University

Other

Odelya E Pagovich

Ronald G Crystal

Maria J Chiuchiolo

Thomas J Kiel

Katie Stiles

Talia Pagovich

Gil Pagovich

Shimon Pagovich

Compositions and methods for eosinophilia in a mammal are provided. In one embodiment, the composition is a viral gene therapy vector, and a single dose of the vector reduces increased numbers of eosinophils in a mammal.

Gene therapy for eosinophilic disorders

This invention is directed to a vector which comprises a promoter operably linked to a nucleic acid sequence encoding a therapeutic gene that blocks allergic reactions. The invention is also directed to a composition comprising the vector and method of using the vector to reduce or inhibit an immune response or allergic reaction to an allergen in a mammal.

Gene therapy to prevent reactions to allergens

This invention is directed to a vector which comprises a promoter operably linked to a nucleic acid sequence encoding the human C1 esterase inhibitor or Factor XII. The invention is also directed to a composition comprising the vector and a method of using the vector to treat or prevent hereditary angioedema.

Adeno-associated virus mediated delivery of C1E1 as a therapy for angioedema

The invention relates to a formula regulation and dispensing system for baby bottles, which allows a controlled volume of formula to be administered through a baby bottle for feeding. This controlled amount of formula allows the user to monitor and regulate the consumption of liquid by an infant between required burpings. Using the invention, the user will know the proper time to burp the baby, thus reducing the occurrence of reflux and other conditions resulting from excess stomach gases.

Growing community of inventors

New York, NY, United States of America

Odelya E Pagovich