Abbott Cardiovascular Systems, Inc.

O Mikael Trollsas

Michael H Ngo

Syed F A Hossainy

Stephen D Pacetti

Lothar W Kleiner

Syed Faiyaz Ahmed Hossainy

David J Sherman

John Joseph Stankus

Dariush Davalian

Benjamyn Serna

Jessica Reneé DesNoyer

Alexander James Sheehy

Yuet Mei Khong

Jessica Renee DesNoyer

The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.

Implantable device with a triblock polymer coating

Embodiments of the present invention encompass methods of forming coatings, particularly coatings for medical devices, and more particularly, for braided or woven medical devices. Embodiments of the present invention encompass the coatings and the coated devices. The coatings may include a polymer and optionally a therapeutic agent.

Coatings for braided medical devices and methods of forming same

Coatings for medical devices, the coatings including albumin, the methods of forming the coatings, and the coated medical devices are disclosed. In preferred embodiments the medical device is a bioabsorbable stent. The albumin coating layer improves the thromboresistance of the device.

Stent with albumin coating for enhanced thromboresistance

The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.

Biodegradable triblock copolymers for implantable devices

Implantable device having a slow dissolving polymer

The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.

Soluble implantable device comprising polyelectrolyte with hydrophobic counterions

The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.

Polymers for implantable devices exhibiting shape-memory effects

An aliphatic polyester polymer for stent coating is described.

Tailored aliphatic polyesters for stent coatings

Implantable device having a coating with a triblock copolymer

Implantable medical devices including a coating having a bioactive agent and a poly(ester amide) polymer. Methods of forming these coatings are also described.

Poly(ester amide)-based drug delivery systems

This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions.

Method of targeting hydrophobic drugs to vascular lesions

A method of forming a coating on a medical device having a controlled morphology is described.

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San Jose, CA, United States of America

O Mikael Trollsas