Universidade Do Minho

Other

Da Costa Martins, Rui Miguel

Carvalho Sousa, Nuno Jorge

Nuno Jorge Carvalho Sousa

Ricardo Alberto Alvarez Osorio

Rui Miguel Da Costa Martins

Ana Sofia Teixeira Esteves

Andreia Cristiana Teixeira De Castro

Patricia Espinheira De Sá Maciel

Ana Luísa De Jales Monteiro De Sousa

Luísa Alexandra Meireles Pinto

Mónica Susana Dias Morais

António Maria Restolho Mateus Pinheiro

João Miguel SEIÇA Bessa Peixoto

PATRÍCIA Espinheira De SÁ Maciel

Biophotonic device for the point-of-care, real-time, non-invasive determination of parameters with diagnostic relevance, in particular an optical system for parameter characterization of an element of body fluid or tissue comprising an optical device which comprises: a light source for emitting light onto the element; and a spectrometer for recording the spectrum of light from the element, said light from the element being of transmittance, reflectance or Raman scattering of the emitted light by said element; the optical system further comprising a data processing module configured to: convert the recorded spectrum by a conversion matrix into a standardized spectrum, wherein said conversion matrix has been obtained by calibrating the optical system spectrum response against a spectrum reference; pre-process the converted spectrum; correlate, for parameter quantification, the converted pre-processed spectrum with pre-obtained spectral bands for each parameter; said spectrum being contained within uv-vis-nir wavelengths. Also methods of operating said system.

Optical system for parameter characterization of an element of body fluid or tissue

Citalopram or escitalopram, pharmaceutically acceptable salts or derivatives thereof for use in the treatment of neurodegenerative diseases The disclosure subject matter is related to the use of citalopram or escitalopram, pharmaceutically acceptable salts or derivatives thereof, in the treatment of neurodegenerative diseases that are positively influenced by the decrease of protein misfolding and/or aggregation, in particular by oral administration.

Citalopram or escitalopram for use in the treatment of neurodegenerative diseases

Growing community of inventors

Oporto, Portugal

Nuno Jorge Carvalho Sousa