The United States Government As Represented by the Department of Veterans Affairs

Universidad Tecnica Particular De Loja

University of Arkansas

Bioventures, LLC

Tocol Pharmaceuticals, LLC

Nukhet Aykin-Burns

Cesar M Compadre

Philip J Breen

Martin Hauer-Jensen

Darin E Jones

Shraddha Thakkar

Omar Malagon

Edgar Ojeda

Raul G Enriquez

E Nathalie Pineda

Sujay Kharade

Yadira Ordonez

Omar Malagon AVILÉS

Provided herein is a tocol rich fraction of rice bran oil deodorized distillate that is shown to be both radioprotective and able to protect against oxidative damage. This fraction may prove an inexpensive and readily available extract that can be used to prepare pharmaceutical compositions for use in protecting against radiation exposure and/or other forms of oxidative stress.

Use of rice bran oil distillate extract for prevention and mitigation of the effects of radiation

Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise &#x3b3;-tocotrienol (GT3) and &#x3b4;-tocotrienol (DT3) in ratios wherein the DT3 is predominate. The compositions are useful for radioprotection and radiomitigation in subjects in need thereof.

Preparation and use of a composition for prevention and mitigation of the effects of radiation

Growing community of inventors

Little Rock, AR, United States of America

Nukhet Aykin-Burns