Octane Biotech Inc.

Lonza Walkersville, Inc.

Lonza Cologne Gmbh

Nuala Trainor

Timothy Smith

Yaling Shi

Eytan Abraham

Kelly Purpura

Timo Gleissner

Erika McAfee

Samatha Bandapalle

Joseph O'Connor

Ann Siehoff

Joseph O'connor

Matthew Hewitt

Chase McRobie

Kevin Middleton

Alexis Pietak

Systems, devices and methods for automatic magnetic separation of magnetized targets in a biological sample are herein disclosed, where they comprise a magnetic field shield/barrier controllably operable to control the magnetic field in terms of reaching and attracting the magnetized targets within the biological sample.

Magnetic separation

The present disclosure provides cell culture chambers for use in automated cell engineering systems, and in particular, cell culture chambers that include improved cell-contacting surfaces. Improved cell-contacting surfaces can include a surface coating that promotes cell growth, adherence, differentiation, maintenance of phenotype, and/or improves transduction; a cell-contacting surface comprising a non-porous, gas-permeable material; as well as other modifications to the cell-contacting surfaces. Cassettes comprising the cell culture chambers are also provided.

Cell culture chamber with improved cell-contacting surfaces

The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.

End-to-end cell therapy automation

Growing community of inventors

Kingston, Canada

Nuala Trainor