Warner-lambert Company

Norman Lloyd Colbry

Jacob Bradley Schwarz

Paul D Johnson

Mark Stephen Plummer

Timothy Thomas Curran

Augustine Tobi Osuma

Ji Zhang

Peter Garth Blazecka

Kevin Edward Henegar

Annise Paige Goodman

Garrett Hoge

Derek Clinton Vrieze

Joseph Richard Bozelak

David Juergen Wustrow

Andrew John Thorpe

Nancy Sue Barta

Zhijian Zhu

Raymond Hudack, Jr

Kristin Knapp Lin

Certain &#x3b2;-amino acids that bind to the alpha-2-delta (&#x3b1;2&#x3b4;) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the &#x3b2;-amino acids.

Amino acids with affinity for the &#x3b1;2&#x3b4;-protein

This invention relates to novel tetrazole and oxadiazalone &#x3b2;-amino acids derivatives of the formula wherein G is wherein Rthrough Rare defined as in the specification, pharmaceutical compositions containing them and their use for the treatment of various central nervous system and other disorders. The cyclopropyl &#x3b2;-amino acids derivatives of this invention exhibit activity as alpha2delta ligands (&#x3b1;2&#x3b4; ligands). Such compounds have affinity for the &#x3b1;2&#x3b4; subunit of a calcium channel.

Tetrazole and oxadiazolone substituted &#x3b2;-amino acid derivatives

2,4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline salts, pharmaceutical compositions containing said salts, methods of treating malaria, and bacterial infections employing said salts and compositions and methods for producing said salts.

2-4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline salts

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Gregory, MI, United States of America

Norman Lloyd Colbry