The Rockefeller University

Norman D Zinder

Peter Model

Jef D Boeke

A method of externalizing proteins from the periplasmic space of gram-negative bacteria and in particular, E. coli and its relatives, comprising utilizing bacteria which have a phage gene, coding for a protein (such as gene III protein) or a mutant bacterial gene (such as a gene coding for a membrane function) which causes perturbation of the outer bacterial membrane resulting in leakage of proteins in the periplasmic space from the cell.

Growing community of inventors

New York, NY, United States of America

Norman D Zinder