Johnson & Johnson Gmbh

Norman A Levin

Leonard L Kaplan

A completely water soluble effervescent denture cleanser tablet containing both an enzyme and one or more active oxygen compounds. The enzyme in said tablet is resistant to premature inactivation by the oxidizing agents in the tablet during storage and in use and therefore has the added enzymatic cleansing power not possessed by conventional tablets containing only the active oxygen compounds. A method for preparing enzyme-containing denture cleanser tablets in which the activity of the enzyme is usefully retained is also described.

Enzyme and active oxygen containing denture cleanser tablet

An admixture of spray dried magnesium lauryl sulfate powder and micronized polyethylene glycol polymers has been found to be an excellent lubricant system in tabletting processes for making water-soluble, effervescent tablets such as tabletted denture cleansers, antacids, analgesics and the like. Such lubricant systems are particularly useful when used in the making of an effervescent denture cleanser tablet.

Water soluble lubricant for tabletting compositions

A water-soluble effervescent, layered denture cleanser tablet containing one or more enzymes in one layer and one or more active oxygen compounds in the other layer and in which the enzyme layer is faster dissolving than the active oxygen layer and is substantially completely dissolved before the dissolution of the active oxygen layer reaches a level which would inactivate the enzyme.

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Somerville, NJ, United States of America

Norman A Levin