Human Metabolome Technologies, Inc.

Other

Gyokikai Medical Corporation

Kawamura, Noriyuki

Noriyuki Kawamura

Yoshiaki Ohashi

Hajime Sato

Kosaku Shinoda

Takamasa Ishikawa

Tamaki Fujimori

Hiroyuki Yamamoto

Kumi Yamaki

A method for treating depression using a biomarker includes measuring a level of phosphoethanolamine in a blood sample collected from a subject, comparing the level of phosphoethanolamine in the blood sample with a predetermined threshold, in response to the level of phosphoethanolamine in the blood sample being below the predetermined threshold, determining that the subject requires a treatment for depression, and treating the subject determined to suffer from depression.

Biomarker of depression, method for measuring biomarker of depression, computer program, and recording medium

Provided is a method for using low molecular weight compounds found in the body as a biomarker for diagnosing depression. Specifically, more than one compound selected from a group comprising the following are used: ADP-ribose, ATP, ADP, AMP, serotonin, tryptophan, kynurenine, SDMA (symmetrical dimethylarginine), threonine, glyceric acid, serine, N-acetylaspartic acid, glutamic acid, trigonelline, creatine, 2-methylserine, sphingosine, homovanillic acid, piperidine, sulfoxidized methionine, pipecolic acid, sphinganine, gamma-butyrobetaine, guanidinoacetic acid, isobutyric acid, creatinine, sarcosine, 3-methylbutyric acid, nicotinamide, betaine, ornithine, carnitine, ethanolamine, phosphoethanolamine, taurine, hypotaurine, aspartic acid, methionine, and tyrosine.

Biomarker for depression, method for measuring a biomarker for depression, computer program, and recording medium

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Tokyo, Japan

Noriyuki Kawamura