Taiho Pharmaceutical Company Limited

Shell Oil Comapny

Kabushiki Kaisha Yakult Honsha

Norio Masuko

Morihiro Mitsuya

Hiroshi Sootome

Tetsuya Sugimoto

Hidekazu Takahashi

Michael John Modic

Yuji Yamada

Masahiko Nishiyama

Yoshikazu Sugimoto

Ken-ichi Matsuo

Keiko Hiyama

Keiji Tanimoto

A novel compound which has an excellent aurora A-selective inhibitory action and is useful as an orally administrable anticancer agent is provided. Also, a novel agent for potentiation of anti-tumor effect of microtubule agonists, which include a taxane anticancer agent, and a combination therapy are provided. A piperidine compound represented by a general formula (I) or a salt thereof: 

Piperidine compound or salt thereof

The present invention is a unique polypropylene copolymer resin composition which comprises a propylene-ethylene copolymer having a melt flow rate of at least 50 g/10 min and an impact modifier which comprises a thermoplastic elastomer of a hydrogenated triblock copolymer which has a specific structure in which a block of a tapered increment of an vinyl aromatic hydrocarbon portion is arranged after the isoprene homopolymer block. Accordingly, the present invention provides a polypropylene resin composition comprising

Polypropylene resin composition with tapered triblock copolymer

Triplex Oligonucleotides targeted to p120

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Tsukuba, Japan

Norio Masuko