Asahi Kasei Kogyo Kabushiki Kaisha

The United States of America As Represented by the Secretary of

The United States of America As Represented by the Department of Health

Norio Iriguchi

John W Boretos

Nobuaki Tsuda

Susumu Isohata

Momoki Sumi

Kyoichi Sasaki

Goro Kanda

Hiroshi Unno

An apparatus and method for separating blood components by means of sedimentation action due to gravitational force are disclosed. The blood to be separated is continuously passed through a flat blood flow channel having a thickness of 20 mm or less and is separated into multiple streams of the separated blood components. An opening for a feed line of the blood is provided at the upstream side of the blood flow channel and at least two openings for discharge lines of the separated blood components are provided at the downstream side of the blood flow channel.

Apparatus and method for separating blood components

A container for the continuous centrifugal separation of platelets component in blood, having a first and a second closed chambers adaptable to be rotated around a rotation axis. Whole blood is continuously introduced into the first chamber. Platelet-rich plasma being obtained as supernatant in the first chamber being discharged through a first outlet port opened at a relatively short distance from the rotation axis and being then introduced into the second chamber. Precipitation in the first chamber being discharged through a second outlet port opened at a relatively long distance from the rotation axis. The consistency of the blood in the first chamber being monitored at a predetermined position which differs from the opened position of the first outlet port and being located between the opened positions of the first and second outlet ports with respect to the distance from the rotation axis. The quantity of the discharge flow through at least one of the first and second outlet ports being controlled so that the consistency of blood maintain a certain constant value. Supernatant in the second chamber is discharged through a third outlet port opened to the second chamber. Platelets component in a high purity content is obtained as precipitation in the second chamber.

Container, apparatus and method for separating platelets

A method of bonding a material to a substrate utilizing a hydrogel adhesive and a source of microwave energy of at least 100 MHz through a waveguide. The bonding may be temporary and frangible by water or may be permanent where it is achieved in a pressure vessel.

Hydrogel adhesives and sandwiches or laminates using microwave energy

An artificial heart valve comprising a semi-rigid framework having three projecting symmetrical struts and open axially therethrough, as well as a polyurethane elastomeric membrane attached to the struts and constituting three leaflets, is formed by molding the framework, including the base and strut, using polyurethane resin; forming the elastomeric membrane, of polyurethane resin which is thin relative to the framework, and forming a thickened commissure along the leading edge of the membrane as well as reinforcing lines radiating from its base; then joining the framework with the elastomeric membrane using an adhesive cement so as to permanently bond the membrane to the framework.

Method of making unitized three leaflet heart valve

A polyurethane heart valve has a semirigid frame composed of a base ring and three struts, and an elastomeric membrane integral and unitary with the frame, the contours of which make up three leaflets of the valve. The leading edges of the leaflets which form the commissure line are reinforced with a narrow elastomer band. The leaflets are further reinforced by radiating lines projected from the frame into the leaflet and which simulate collagen formation in natural leaflets. In addition, the transition between the frame and the leaflets is tapered.

Unitized three leaflet heart valve

A microwave oven comprises a heating element which produces heat by absorption of microwave radiation and on which is placed a material to be cooked with the interposition of a material support therebetween. If required, the heating element is disposed on a heat insulating body. A shield cover is arranged on the support for enclosing the material to be cooked placed on the support and for limiting the amount of microwave radiation which is allowed to be incident on the material from the exterior thereof. The material to be cooked is internally heated upon irradiation with the radiation and at the same time the heating element produces heat which is applied to the surface of the material through the material support. When the material support comprises a metal plate, an electric insulating body which prevents a spark discharge is arranged between the shield cover and the metal plate.

Growing community of inventors

Fuji, Japan

Norio Iriguchi