Takeda Pharmaceutical Company Limited

Orizuru Therapeutics, Inc.

Noriko Yamazoe

Masaki Hosoya

Taro Toyoda

Masanobu Shoji

Yuya Kunisada

Junji Yamaura

Shuhei Konagaya

Hideyuki Hiyoshi

Taisuke Mochida

An object of the present invention is to provide a novel method for producing a biological tissue-like structure comprising differentiated cells induced from pluripotent stem cells, and the present invention provides a method of forming a biological tissue-like structure together with host-derived blood vessels and connective tissue by transplanting a composition in which cells derived from pluripotent stem cells are disposed to be dispersed in a biocompatible material to induce the differentiation of the cells.

Method for producing biological tissue-like structure

The present invention provides a method of more efficiently producing pancreas cells, particularly pancreatic hormone-producing cells, a method of stably producing pancreas cells in a large amount by more efficiently inducing differentiation of stem cells into pancreas cells, a medicament containing a pancreas cells and a screening method using the cells. A method of producing pancreatic hormone-producing cells, including subjecting stem cells to the following steps (1)-(4):

Method for manufacturing pancreatic-hormone-producing cells

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Kanagawa, Japan

Noriko Yamazoe