Nihon Medi-Physics Company, Limited

Kabushiki Kaisha Toshiba

Hokkaido University

Kagoshima University

Sumitomo Pharma Co., Ltd.

Norihito Nakata

Yoshinari Shoyama

Akio Hayashi

Yuji Ito

Yuki Okumura

Mitsuhiro Matono

Toshio Aoki

Hiroki Matsumoto

Yuji Kuge

Masato Kiriu

Nobuya Kobashi

Takayuki Murakami

Masaaki Matsumoto

Eriko Nagata

Songji Zhao

Yasushi Ochiai

Ken-Ichi Nishijima

The present invention relates to an IgG-binding peptide comprising a ligand capable of binding to a radioactive metal nuclide, an IgG-binding peptide labeled with a radioactive metal nuclide, a conjugate of the IgG-binding peptide and IgG, and a radionuclide imaging agent or a diagnostic agent for cancer comprising the IgG-binding peptide or the conjugate, etc.

Site-specific radioisotope-labeled antibody using IgG-binding peptide

The RI-labeled anti-MUC5AC humanized antibody of the present invention is a conjugate of a chelating agent chelated with a radionuclide and an antibody (the radionuclide is a metal nuclide that emits &#x3b1; particle or positron, and the antibody is a humanized antibody specifically binding to MUC5AC), and is superior in specificity for MUC5AC and accumulation in tumor. Therefore, it is extremely useful for the treatment and/or diagnosis of diseases in which MUC5AC is overexpressed, particularly cancer.

Ri-labeled humanized antibody

A valve control system for a steam turbine that decrease in effective power as well as secure control stability in the event of an electric power system accident is provided. A valve control system for a steam turbine includes an accident detection unitwhich detects an occurrence of an electric power system accident, a first selection unitwhich selects, from a plurality of control valves() which adjust a volume of steam flowing into a steam turbine, control valvesto be rapidly closed according to a scale of the accident detected, and a normal control circuitwhich continues normal pressure or speed control by the control valveswhich are not selected.

Valve control system and valve control method for steam turbine

The present invention is a compound represented by the following formula (1) or a salt thereof. In the formula (1), Rdenotes a hydrogen atom, a methyl group, or a hydroxymethyl group, and n is an integer of 1 or 2. 

Radioactive fluorine-labeled compound

Growing community of inventors

Tokyo, Japan

Norihito Nakata