Canon Kabushiki Kaisha

Mie University

Norihiro Nishimura

Takeshi Miyazaki

Toshio Tanaka

Kohei Watanabe

Yasuhito Shimada

Taichi Shintou

Tsuyoshi Nomoto

Yuhei Nishimura

Masashi Hirose

Taketoshi Okubo

Kaoru Takahashi

Provided is a novel probe for a biological specimen for labelling by itself and clearly visualizing one of a specific cell and a specific cell organ in a living body, the probe having excellent spectral characteristics and exhibiting excellent storage stability. The probe for a biological specimen contains, as an active agent, at least one kind of compound represented by a general formula (I). 

Probe for a biological specimen and labelling method and screening method using the probe

The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as exposure of an ocular tissue or injection of a staining agent into the ocular tissue or a nerve tissue linking to the ocular tissue, a method of noninvasively labeling an intraocular tissue of a living individual, and a screening method using the labeling composition for the intraocular tissues. The composition contains a compound capable of labeling at least a photoreceptor cell layer of a retina, wherein the compound is a staining compound having a particular structure as a partial structure thereof.

Labeling composition for intraocular tissue, labeling method of intraocular tissue, and screening method

A method of arranging a large number of living bodies, such as cells, embryos, or organisms rapidly, individually, and one by one, a holding sheet for the method, and a device for processing the living bodies. The method of holding living bodies includes using a sheet in which multiple through-holes with a size capable of holding one of the target living bodies, but not capable of holding two or more of the living bodies, are provided, to thereby arrange and hold the living bodies one by one in the multiple through-holes in the sheet together with a liquid.

Living body holding method, living body test method, living body growing method, living body holding sheet, and living body processing device

Provided are a novel probe for a hair cell for clearly identifying various conditions of a hair cell, and a labelling method for a hair cell using the probe for a hair cell, more particularly, a probe for a hair cell containing, as an active agent, a staining compound represented by the general formula (I) 

Probe for a hair cell, and labelling method for a hair cell using the probe for a hair cell

Growing community of inventors

Tsu, Japan

Norihiro Nishimura