Massachusetts Institute of Technology

Nopphon Weeranoppanant

Klavs F Jensen

Andrea Adamo

Jie Chen

Ping Zhang

Timothy F Jamison

Allan Stuart Myerson

David R Snead

Jean-Christophe Monbaliu

Torsten Stelzer

Mohsen Behnam

Shin Yee Wong

Eve Marie Revalor

Patrick Louis Heider

Alexander P Clayton

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients

Pressure control in fluidic systems is generally described. In some cases, a system comprises a fluid-permeable (e.g., liquid-permeable) medium and a pressure regulator. The medium and the pressure regulator can be positioned between a first fluidic channel and a second fluidic channel. The medium is arranged, in certain cases, such that fluid (e.g., liquid) can be transported from the first fluidic channel, through the medium, and into the second fluidic channel. In certain cases, when a first pressure within the first fluidic channel is below a sum of the permeability pressure differential of the medium with respect to the fluid and a second pressure within the second fluidic channel, the fluid is substantially prevented from being transported through an outlet of the first fluidic channel.

Pressure control in fluidic systems

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Muang, Thailand

Nopphon Weeranoppanant