Pall Corporation

Noel Tod Borton

Jeffrey Francis Kane

Daniel F Bischof

John R Chapman

Chong-Son Sun

Robert E Herman

Mark Alexander Sutter

A method for purifying conventionally treated blood plasma to remove substantially all residual leukocytes while maintaining useful flow rates for medically useful amounts of plasma utilizes a disposable, heat-sterilizable filter employing one or more depth-type prefilters and at least one intermediate hydrophilic microporous membrane followed by at least one final hydrophilic microporous membrane having a smaller pore size than the intermediate membrane within a common housing. The purified plasma is preferably subjected to chemical treatment to destroy infectious agents such as hepatitis and HIV.

Method for purifying blood plasma and apparatus suitable therefor

Use of a disposable filtration capsule with a non-occluded membrane filter element in the place of a standard spiral wound cartridge allows for the more rapid and quantitative filtration, recovery, and quantitation of microorganisms in liquid, particularly surface waters, well water, tap water, and the like. The capsule allows a severe reduction in the water sample size tested, substantially minimizes risks of cross-contamination, and provides a leak-proof vessel for shipment. Risk of infection of laboratory personnel and time of analysis are both reduced. Costs of measuring contamination by microorganisms such as Giardia and Cryptosporidium is lowered significantly while increasing the accuracy and dependability of the measurement.

Filtration device for quantitation of microorganism contaminated liquids

Method for quantitation of microorganism contamination of liquids

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Chelsea, MI, United States of America

Noel Tod Borton