Mect Corporation

Nissin Shokuhin Kabushiki Kaisha

Nobuyuki Kibushi

Takayuki Ishii

Tomoya Ogawa

Mamoru Sugimoto

Masaaki Numata

Makoto Tanaka

Kenkichi Tomita

Ryoichi Osawa

Makiko Kasano

Tae Yasunaga

Naokazu Sugiyama

Isao Suda

Mariko Ishii

Satoshi Yoshida

Motoaki Goto

Kei Sugai

Yumiko Noda

Hutoshi Nishikawa

A glycoside represented by formula (I), wherein dexamethasone or betamethasone is the aglycon and the 21-position is substituted by a simple sugar or an acylated sugar selected from the group consisting of glucose, galactose, mannose, rhamnose, fucose, N-acetylglucosamine, N-acetylgalactosamine, galacturonic acid, glucuronic acid and sialic acid. ##STR1##

21-Substituted steroid compound

An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts, thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

Method for modulating the immune system

An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

Methods for inhibiting the chemotaxis of neutrophils

Anti-inflammatory agent

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Iruma, Japan

Nobuyuki Kibushi