Sumitomo Chemical Company, Limited

Daicel Chemical Industries, Ltd.

Asahi Kasei Chemicals Corporation

Nobuya Itoh

Kazunobu Konishi

Hiroyuki Asako

Kenji Matsumura

Ryuhei Wakita

Masatoshi Shimizu

Junji Kurokawa

The disclosure provides 2-deoxy-scyllo-inosose reductases derived from a microorganism having the ability to utilize (&#x2212;)-vibo-quercitol, recombinant vectors and transformants comprising genes encoding the same, and methods of use thereof.

2-deoxy-scyllo-inosose reductase

A gene containing a DNA having the nucleotide sequence encoding any one of the amino acid sequences of the following (a) to (e):

Reductase gene and use of the same

There are provided a polynucleotide sequence coding for an amino acid sequence capable of preferentially producing (S)-4-bromo-3-hydroxy-butanoate by asymmetrically reducing 4-bromo-3-oxobutanoate, A DNA construct having a promoter in operative linkage with the polynucleotide sequence, a recombinant vector containing the polynucleotide sequence, a transformant, a recombinant vector and the like.

Process for producing optically active 4-halo-3-hydroxybutanoate

Methods are provided to produce highly concentrated dihydroxyacetone-3-phosphate efficiently by a simple catalytic reaction of dihydroxyacetone with the bacterial cells transformed with the gene encoding a dihydroxyacetone kinase or the dihydroxyacetone kinase produced by said bacterium.

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Toyama, Japan

Nobuya Itoh