Hisamitsu Pharmaceutical Company, Inc.

Nobuo Tsutsumi

Masakazu Shigiishi

Shigeo Kusumi

Takafumi Miyachika

Shigeo Ohta

Kazunosuke Aida

Naruhito Higo

Hideaki Iwahashi

Terumitsu Kaiho

Tetsurou Tateishi

Shigeo Ota

Tetsuro Tateishi

Takeshi Ito

Takaaki Terahara

Shinji Yamasoto

Kiyomi Tsuruda

Takaaki Yoshinaga

Kenichi Yamashita

Kazunori Muta

Takahito Yoshizaki

Junichi Kubo

Tomomi Okada

Kouji Tanaka

Shigeki Hayashi

A method for producing a patch comprising a support layer and an adhesive agent layer arranged on at least one surface of the support layer, the method comprising:

Method for producing patch, patch and package

A pressure-sensitive adhesive tape package is provided. The pressure-sensitive adhesive tape package accommodates an adhesive tape having a support and an adhesive agent layer provided on one surface of the support, the adhesive tape being bent into a first portion and a second portion such that the adhesive agent layer faces outward. Moreover, the pressure-sensitive adhesive tape package can include a first release sheet releasably attached to the adhesive agent layer of the first portion of the adhesive tape, and a second release sheet releasably attached to the adhesive agent layer of the second portion of the adhesive tape to seal the adhesive tape with the first release sheet between the first and second release sheets. In this configuration, the conventionally existing package can be eliminated. Moreover, when the second release sheet is removed from the adhesive agent layer of the second portion of the adhesive tape, half of the adhesive agent layer is exposed.

Pressure-sensitive adhesive tape package

A patch permitting division of only its release sheet by simply pulling right and left, wherein detachment of the release sheet is easy. There is provided a patch comprising a stretchable support, a plaster applied substantially all over one major surface of the support and a release sheet attached to the whole surface of the plaster wherein only the release sheet is divided at a division zone by simply pulling right and left, and wherein one or two or more precut parts that open when the patch is pulled right and left are disposed in the neighborhood on the division zone.

Patch having easily detachable release sheet

Patch and method for producing the same

A method for producing a patch having a high skin penetrability and a high pharmaceutical physical properties such as adhesion and cohesiveness, and a long-term storability. The patch is produced by first obtaining an adhesive agent layer composition containing oxybutynin and/or salt thereof as a drug, an acrylic-based polymer and/or a rubber-based polymer as an adhesive base agent, liquid paraffin, an organic acid, and a tackifier; heating the adhesive agent layer composition at a temperature in a range from a melting point of the drug to a temperature higher than the melting point by 10&#xb0; C. for 2 to 24 hours; and slowly cooling the heated adhesive agent layer composition to obtain the adhesive agent layer comprising the drug at a supersaturated concentration in a dissolved form.

Provided is an adhesive patch including a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a woven fabric knitted in stockinette stitch on both sides having two or more rows of crimped polyethylene terephthalate multifilament yarns, the adhesive layer contains 25 to 50% by mass of a liquid organic ingredient and 25 to 50% by mass of a thermoplastic elastomer based on the total mass of the layer and contains 10% by mass or more of methyl salicylate as the liquid organic ingredient based on the total mass of the layer, and the storage elastic modulus (G') of the adhesive layer is 30000 to 75000 Pa at 10 rad/s and 37&#xb0; C.

Adhesive patch

Packaging box

Growing community of inventors

Tokyo, Japan

Nobuo Tsutsumi