Teikoku Seiyaku Kabushiki Kaisha

Chiesi Farmaceutici S.p.a.

Nobuko Inoue

Takahiko Wato

Yukihiro Tada

Teruo Hama

Toshikuni Kawazi

Masahiro Ono

Shin-ichi Hisaichi

A preparation for intermittently releasing an active agent which comprises a laminated combination of a release-controlling layer and a pharmaceutically active agent-containing layer wherein one or more of pharmaceutically active agent layers are incorporated into said release-controlling layer. The preparation in accordance with the present invention can intermittently control the release of the active agent to decrease a dosage time and is applicable to the mucous membrane or gingivae within the oral cavity.

Preparation for intermittently releasing active agent applicable to oral

A plaster, which can be used in the prevention of attacks of bronchial asthma and in the treatment of bronchitis, comprises an adhesive base composition comprising a macromolecular substance and a sequestering agent and containing salbutamol, and a support for supporting the adhesive base composition spread thereon, and a method of producing the plaster are provided.

Salbutamol-containing plaster and method of producing same

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Kagawa, Japan

Nobuko Inoue