Ajinomoto Co., Ltd.

Japanese Foundation for Cancer Research

Nobukazu Kashima

Hiroshi Matsui

Tadatsugu Taniguchi

Junji Hamuro

Haruo Sugano

Masami Muramatsu

Ryota Yoshimoto

Koji Mitsugi

A gene coded for a polypeptide which possesses interleukin-2 is isolated, and connected with a vector DNA which is capable of replicating in a procaryotic or eucaryotic cell at a position downstream of a promoter gene in the vector obtaining a recombinant DNA, with which the cell is trans-formed to produce interleukin-2.

Gene coded for interleukin-2 polypeptide, recombinant DNA carrying the

A gene coded for a polypeptide which possesses interleukin-2 is isolated, and connected with a vector DNA which is capable of replicating in a procaryotic or eucaryotic cell at a position downstream of a promoter gene in the vector obtaining a recombinant DNA, with which the cell is transformed to produce interleukin-2.

Gene encoding interleukin-2 polypeptide, recombinant DNA carrying the

Recombinant human Interleukin-2 (IL-2) polypeptides are provided. The polypeptides are produced by expression of suitable nucleic acid molecules in transformed host cells such as E. coli.

Unglycosylated human interleukin-2 polypeptides

An immunopropylactic and immunotherapeutic agent comprising human interleukin 2 of human cellular origin is disclosed along with a method of producing the agent.

Immunoprophylactic and immunotherapeutic agents

A gene coded for a polypeptide which possesses interleukin-2 activity is isolated, and connected with a vector DNA which is capable of replicating in a procaryotic or eucaryotic cell at a position downstream of a promoter gene in the vector obtaining a recombinant DNA, with which the cell is transformed to produce interleukin-2.

Growing community of inventors

Yokohama, Japan

Nobukazu Kashima