Otsuka Pharmaceutical Factory, Inc.

Other

Senju Pharmaceutical Co., Ltd.

Nobuaki Sumiyoshi

Katsuhiro Inada

Yoshiyuki Kimura

Seiichiro Iguchi

Mitsuhira Nishio

Junji Kaga

Koichi Muraoka

Hiroaki Yamamoto

Isamu Tateishi

Seiji Tani

Hitoshi Mori

Yasuhiro Mitsumoto

Yasushi Morimoto

Masaru Kobayashi

Shigeaki Arita

Masamori Sano

Yosuke Samejima

A reduced-dissolved-oxygen-content drug solution produced by filling and sealing the drug solution in a drug solution container () formed of a plastic material having an oxygen permeability of not lower than 200 cm/m&#xb7;24 h&#xb7;atm at 25&#xb0; C. at 60% RH within 12 hours after a steam sterilization process or a hot water sterilization process and having a steady-state oxygen permeability of not higher than 100 cm/m&#xb7;24 h&#xb7;atm at 25&#xb0; C. at 60% RH, subjecting the drug solution container to the steam sterilization process or the hot water sterilization process, and storing the drug solution container in an environment having deoxidization means for reducing the dissolved oxygen concentration of the drug solution to not higher than 2 ppm when the oxygen permeability of the plastic material reaches the steady-state level.

Drug solution having reduced dissolved oxygen content, method of producing the same and drug solution containing unit having reduced dissolved oxygen content

Container

There is provided an aseptic combination preparation to be mixed at the time of use, characterized in that the same medicinal ingredients are divided and preserved in two or more chambers. The aseptic combination preparations according to the present invention are a mixing type at the time of their use and are useful as infusions, various dialysis fluids, intraocular perfusion/washing solutions, coronary perfusion solutions, myocardial protective solutions, peritoneal lavage solutions, solutions for organ preservations, etc., which can eliminate adverse effects caused by medical error on a living body.

Aseptic combination preparation

A packaged ocular irrigating solution bag, which comprises a gas-permeable plastic multiple compartment bag and a gas-impermeable plastic packaging member for packaging the bag and in which an oxiglutatione-containing solution or solid preparation is enclosed in one compartment and a bicarbonate ion solution is enclosed in another compartment and the space between the bag and the packaging member has a carbon dioxide gas atmosphere.

Method of packaging ocular irrigating solution

Packaged ophthalmic perfusate and cleaning fluid bag

Growing community of inventors

Naruto, Japan

Nobuaki Sumiyoshi