Toyo Jozo Kabushiki Kaisha

Asahi Kasei Kogyo Kabushiki Kaisha

Nobuaki Nakagawa

Susumu Watanabe

Kikuo Kotani

Kunio Ohyama

Tadashiro Fujii

Toshiharu Noda

Shigeo Katsuragi

Kaoru Morita

Shigeru Ikuta

Miyuki Tanabe

Sadami Kobari

Akihiro Hino

Masahiko Taniuchi

Hisanori Endo

Hiroyuki Takano

Akio Sato

Tsuneo Okuyama

A diploid hybrid bakers' yeast belonging to Saccharomyces cerevisiae having at least strong fermentative ability of non-sugar bread dough and strong freeze-resistance and frozen bread dough containing the same are provided.

Freeze resistant bakers' yeast

A novel 25-hydroxy vitamin D.sub.3 amino acid derivative of the formula ##STR1## wherein R.sub.1 is C.sub.1-10 alkylene, is produced by removing a protective group for the amino group, e.g. 9-fluorenylmethyloxycarbonyl, in the presence of a base in an inert solvent. A radioisotope iodine-labeled residue is then attached to the amino group to produce a derivative useful in the assay of 25-hydroxy vitamin D.sub.3 in a specimen.

25-hydroxy vitamin D.sub.3 derivatives, process for their production,

A novel 25-hydroxy vitamin D.sub.3 amino acid derivative of the formula ##STR1## wherein R.sub.1 is C.sub.1-10 alkylene, is produced by removing a protective group for the amino group, e.g. 9-fluorenylmethyl-oxycarbonyl, in the presence of a base in an inert solvent. A radioisotope iodine-labeled residue is then attached to the amino group to produce a derivative useful in the assay of 25-hydroxy vitamin D.sub.3 in a specimen.

Apparatus for performing an immunoassay, comprises in combination a reaction tube closed at its bottom, and in the reaction tube a molded element having on its surface material having specific binding ability for a component in a liquid specimen to be assayed. The shape of the surface of the element adjacent the interior surface of the tube is the complement of the shape of the interior surface of the tube. A spacer rib is provided on the element, in contact with the interior surface of the tube. This rib holds the element in such position in the tube that the surfaces of complementary shape of the element and tube are shaped from each other a small but constant distance. A thin layer of constant thickness of a liquid specimen for immunoassay is thus receivable between the complementary surfaces. This arrangement increases the contact surface of the liquid medium in the reaction tube by the element, by establishing a homogeneous uniform layer of liquid medium. This avoids the need for stirring and shaking and reduces the required volume of the specimen to be assayed.

Element for immunoassay

Process for the preparation of antibodies

Peptides for assaying human parathyroid hormone

C-Terminal fragment of human chorionic gonadotropin

A polyfunctional disulfide compound, useful as a cross-linking reagent having S--S exchange reactivity, of the formula ##STR1## wherein R is 2-benzothiazolyl or 2-pyridyl-N-oxide and X is a spacer group having an alkylene group directly bonded to each S--S group.

Polyfunctional disulfide compounds having S--S exchange reactivity

A disulfide derivative, having S--S exchange reactivity, of the formula

Disulfide derivatives having S--S exchange reactivity

A disulfide compound of a carrier, having S--S exchange reactivity, of the formula

Disulfide compounds of a carrier, having S--S exchange reactivity

Growing community of inventors

Shizuoka, Japan

Nobuaki Nakagawa