Chi2gel Ltd.

Chit2gel Ltd.

Noah Ben-Shalom

Abraham Patchornik

Zvi Nevo

Dror Robinson

A chitosan composition which forms a hydrogel at near physiological pH and 37&#xb0; C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37&#xb0; C., that includes at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions.

Injectable chitosan mixtures forming hydrogels

A chitosan composition which forms a hydrogel at near physiological pH and 37&#xb0; C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37&#xb0; C., comprising at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions.

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Tel Aviv, Israel

Noah Ben-Shalom