University of California

Versatile Power, Inc.

Noah A Wilson

David W Deamer

Mark Albert Akeson

William Dunbar

Roger Jinteh Arrigo Chen

Alexandr Ikriannikov

David Hoffman

Kathy Lieberman

Kate Lieberman

Daniel Branton

Seico Benner

Robin Abu-Shumays

Nicholas Hurt

William B Dunbar

Roger Jinteh Chen

Seiko L Endo

Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.

Compositions, devices, systems, and methods for using a nanopore

Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (&#x2dc;&#x3e;50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.

Nucleotide sequencing using an array of independently addressable nanopores

Methods for using a nanopore

A circuit includes a first input terminal for receiving a first pulsed voltage and a second input terminal for receiving a second pulsed voltage. The circuit further includes a load and an LC filter. The LC filter includes a coupled inductor pair that includes a first winding and a second winding magnetically coupled to each other. The first winding is coupled between the first input terminal and the load, and the second winding is coupled between the second input terminal and the load. A frequency of a first current flowing through the first winding is increased by the second pulsed voltage applied to the second winding.

Differential output inductor for class D amplifier

The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore. The devices and methods are also used to determine rapidly (&#x2dc;&#x3e;50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.

Growing community of inventors

Felton, CA, United States of America

Noah A Wilson