Southwest Research Institute

Nitin Nitin

Heather Shannon Hanson

Stephen Thomas Wellinghoff

Xingguo Cheng

Jorge Gianny Rossini

Kwai S Chan

Jenny Finkbiner

James D Oxley

Daniel P Nicolella

The present disclosure relates to methods of facilitating bone growth. The method may include positioning a device around at least a portion of a bone exhibiting a defect, the device capable of retaining bone segments and micro-structured particles. The method may also include applying micro-structure particles within the device to the defect, wherein each of the micro-structure particles include at least one pore therein. In addition, the method may include aligning at least a portion of the micro-structure particles and applying a polymer to the particles and solidifying the polymer.

Micro-structure particles for load bearing bone growth

A medical implant for drug delivery comprising an inner layer of polymer material including a drug dispersed therein and an outer layer which may then mediate the release of the drug in a controllable manner. The outer layer may adhere and/or penetrate the underlying layer and offer a protective coating along with improved mechanical strength along with the ability to hydrate and become permeable to water and allow for drug release.

Coating for medical implants

The present disclosure relates to microcapsules that include a shell material and a core material. The core material of the microcapsules contains an environmentally sensitive luminescent colorant which exhibits characteristics of an emitted wavelength bandwidth, a peak intensity for emission and a time for luminescence decay, one or more of the characteristics capable of changing upon exposure to a given environment, and a luminescent standard which exhibits characteristics of an emitted wavelength bandwidth, a peak intensity for emission and a time for luminescence decay, one or more of the characteristics do not change upon exposure to said given environment.

Fluorescent monitoring of microcapsule oxidation

The present disclosure is directed at methods and apparatus to evaluate and monitor healing progress of wound and/or to generate data to modify or identify a treatment protocol. Fluid exudate removed from the wound by a negative pressure therapy device may now be analyzed to identify the progress of wound healing, such as whether healing is progressing in a positive manner or experiencing one or more impediments. The fluid exudates may be specifically analyzed for one or more analytes indicative of one or more of the biochemical reactions that may occur during wound recovery. In addition, one may separately utilize optical sensors integrated into a dressing enclosure, optionally in those dressings employed in a negative pressure therapy device. Such optical sensors may then illuminate the wound and collect information regarding the wound via a light scattering type response.

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Vacaville, CA, United States of America

Nitin Nitin