Impulse Dynamics Nv

Metacure Limited

Neovasc Medical Ltd.

Metacure N.v.

Impulse Dynamics (israel) Ltd.

Nissim Darvish

Shlomo Ben-Haim

Yuval Mika

Maier Fenster

Bella Felzen

Isaac Shemer

Ziv Belsky

Mika Yuval

Benny Rousso

Bella Felsen

Ilan Shalev

Jonathan Tsehori

Dov Malonek

Andre G Routh

David Prutchi

Itzhak Shemer

Shmuel Ben-Muvhar

Mike Yuval

Tami Harel

Edward Haluska

Melina Flesler

Yaakov Ben Arie

Judith Kornfeld

Yehuda Snir

Itzhak (Itsik) Shemer

Shiomo Ben-Haim

Itzik Shemer

Offer Glasberg

Walid Haddad

Richardo Aviv

Yaakov Haham

Shmuel Ben Muvhar

Fenster Maier

Itzhak (Itrik) Shemer

Iian Shalev

A flow reducing implant for reducing blood flow in a blood vessel having a cross sectional dimension, the flow reducing implant comprising a hollow element adapted for placement in the blood vessel defining a flow passage therethrough, said flow passage comprising at least two sections, one with a larger diameter and one with a smaller diameter, wherein said smaller diameter is smaller than a cross section of the blood vessel. A plurality of tabs anchor, generally parallel to the blood vessel wall, are provided in some embodiments of the invention.

Methods for treating abnormal growths in the body using a flow reducing implant

A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by at least 5%.

Electrical muscle controller

A method of promoting the healing of a lesion in a smooth muscle (), comprises selecting a smooth muscle portion having a lesion, and applying a non-excitory electric field () to the portion, which reduces the mechanical activity of the portion.

Methods and devices for modifying vascular parameters

A method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart, comprising at least a portion having an activation, and applying a non-excitatory electric field having a given duration, at a delay after the activation, to the portion, which causes the force of contraction to be increased by a least 5%.

A method for improving the tissue oxygenation of a subject by identifying diminished blood flow in a blood vessel and deploying a flow reducing implant in a blood vessel. The flow reducing implant comprises a hollow element adapted for placement in the blood vessel defining a flow passage therethrough, said flow passage comprising at least two sections, one with a larger diameter and one with a smaller diameter, wherein said smaller diameter is smaller than a cross section of the blood vessel.

According to a method and device for modulating intracellular calcium concentration in biological tissue, a stimulation probe is applied to the tissue, a non-excitatory stimulation pulse is generated, and the pulse is conveyed to the stimulation probe. In one embodiment concerning cardiac tissue, a stimulation probe is applied to a patient's heart, a signal is received from at least one sensor responsive to the patient's cardiac muscle activity, a non-excitatory stimulation pulse responsive to the signal is generated, and the pulse is conveyed to the stimulation probe.

Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue

Methods for controlling labor and treating menstrual cramps in uterine muscle

Methods of using flow reducing implants for treatment of abnormal growths in the body are described. In embodiments of the claimed subject matter, a source blood vessel feeding the abnormal growth is first determined, and a flow reducing implant is then inserted into the source blood vessel to reduce the blood flow through the source blood vessel. The flow reducing implant includes at least one flared section for contacting a blood vessel wall, and at least one narrowed section defining a flow passage. Anchor tabs that lie generally in a plane of the flared section may also be employed.

Blood glucose level control

A method of modifying the force of contraction of at least a portion of a heart chamber is provided. A non-excitatory electric field of given duration is applied, at a delay after an activation of the heart, which increase the force of contraction by at least 5%. Apparatus is also provided for pacing with hemodynamic improvement. Circuitry applies an extended pacing signal to electrodes to pace the heart, the extended pacing signal having an overall duration greater than 8 ms from a time of initiation of application of that portion of the signal that initiates action potential propagation. The signal includes a train of biphasic pulses having pulse durations of at least 1 ms, and the signal has an amplitude that is at least three times as great as a threshold for pacing the heart and that is sufficient neither for cardioversion nor for defibrillation. Other embodiments are also described.

Electrical muscle controller and pacing with hemodynamic enhancement

Growing community of inventors

Haifa, Israel

Nissim Darvish