Beckman Coulter, Inc.

Nir Shapir

Hashem Akhavan-Tafti

Renuka De Silva

Wenhua Xie

Michael Salvati

James D Mendoza

Bruce H Odegaard

Dean G Binger

Ying Chen

Terri McLernon

Dean Binger

Terri Mclernon

Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.

Solution phase homogeneous assays

Growing community of inventors

Falcon Heights, MN, United States of America

Nir Shapir