Hikma Pharmaceuticals USA Inc.

Insys Development Company, Inc.

Radius Pharmaceuticals, Inc.

Hoffmann-la Roche Inc.

F. Hoffmann-la Roche Ag

Fresh Cut Development, LLC

Ningxin Yan

Venkat R Goskonda

Thrimoorthy Potta

Chandeshwari Chilampalli

Kiran Amancha

Eshwaran Narayanan

Craig Bastian

Rachana Inavolu

Kiran Kumar Vangara

Hung Q Nguyen

Shivani Chilampalli

Huaguang Li

Ning Shan

Rajesh Wakaskar

Andrew B Schlinkert

Min Wu

Edwin A Baldwin

Zhongjiang Jia

Urs Schwitter

Ralph Diodone

Duk Soon Choi

Rudolf Benz

Choi Duk Soon

Bharat Patel

Daniela Bockenstedt

Rajesh Pandya

The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid overdose, opioid dependence, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention intranasally to a patient in need thereof. Further, the invention provides a method of treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally the naloxone formulations of the present invention.

Liquid naloxone spray

The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.

Stable cannabinoid formulations

The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.

Epinephrine spray formulations

Sublingual formulations containing an opioid, preferably, fentanyl or a pharmaceutically acceptable salt or ester thereof, naloxone or a pharmaceutically acceptable salt or ester thereof, and a terpene; as well as methods of treating pain by administering the formulations of the invention to a patient in need thereof.

Sublingual opioid formulations containing naloxone

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Chandler, AZ, United States of America

Ningxin Yan