Avaya Inc.

Columbia University

Nina Tandon

Joann J Ordille

Qian Yang

Gordana Vunjak-Novakovic

Patrick Tendick

Keith Yeager

Sarindr Bhumiratana

Donald O Freytes

Warren L Grayson

Kacey Ronaldson

Qun Wan

Elisa Cimetta

Amandine Godier-Furnémont

George Eng

Robert Maidhof

An integrated system for detecting safety and/or efficacy issues related to potential drug compounds by combining tissue maturation, imaging and electrophysiology measurements, at high throughput, with high signal to noise ratio. Testing includes cardiotoxicity screening, drug screening, and screening for cardiogenic factors via on-line physiological measurements.

System and method for high-throughput assessment of cellular cardiotoxicity, drug screening, and cardiogenic factors via online physiological measurements

Disclosed are bioreactor devices, systems and methods. A bioreactor system can include one or more bioreactor modules that can be individually controllable and identifiable. A bioreactor module can be connected to one or more functional modules such as a pump module, a stimulation signal generation module, a motor module, a mechanical transmission module, a gas exchange module, a temperature module, a humidity module and/or a COmodule, among others. The bioreactor and functional modules can include standard or universal connectors to facilitate connection and movement of modules. The bioreactor system can be controlled and/or monitored by a controller that can individually identify and control each connected module and that can be adapted to collect signal data from sensors embedded in any of the modules.

Bioreactor, devices, systems and methods

Methods and apparatus are disclosed for notifying one or more users of information having a plurality of attributes. A plurality of subscribable objects are provided to one or more users, where each subscribable object comprises one or more attributes as required attributes and zero or more of the attributes as optional attributes. Subscription requests are received from one or more of the users based on at least one of the subscribable objects. The subscribable objects are based, for example, on a set of predefined templates. The predefined templates identify each of the plurality of attributes as a required attribute or an optional attribute. Each of the attributes is presented to a user using a display format selected based on a cardinality of the corresponding attribute.

Method and apparatus for a publish-subscribe system with templates for role-based view of subscriptions

Methods and apparatus are provided for subscribing to dynamic attributes. One or more users are notified of information having a plurality of attributes, including at least one dynamic attribute. According to one aspect of the invention, a user can enter a subscription request to be notified when the at least one dynamic attribute changes a value. For example, the subscription request can notify the user when the dynamic attribute (i) changes a value to one or more predefined values; (ii) changes to satisfy a user specified condition; or (iii) changes to a value within a specified range of values. The subscription request can optionally include one or more temporal conditions. For example, the temporal conditions can evaluate whether the dynamic attribute satisfied a value constraint during a given time interval.

Method and apparatus for notifying a user of a predefined changes to dynamic attributes

Methods and apparatus are disclosed for notifying one or more users of information, where the information has a plurality of attributes. A plurality of subscribable objects are provided to one or more of the users, where each of the subscribable objects comprises one or more of the plurality of attributes as required attributes and zero or more of the attributes as optional attributes. Subscription requests are received from one or more of the users based on at least one of the subscribable objects. The plurality of subscribable objects are based, for example, on a set of predefined templates. The predefined templates identify each of the plurality of attributes as a required attribute or an optional attribute. Each of the attributes is presented to a user using a display format selected based on a cardinality of the corresponding attribute. For example, the display format for a given attribute may comprise one or more of a user entry, a scrollable list and a check box.

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New York, NY, United States of America

Nina Tandon