Biotronik Ag

Nina Foh

Alexander Rzany

Wilhelm Erdbruegger

Bernhard Hensel

Giuseppe Pisani

Matteo Astorino

Davide Mogentale

Judith Flore Solowiej

Kilian Badrutt

Christine Mueller

Daniel Niopek

A method for preparing tissue, in particular pericardial tissue, in particular for a heart valve prosthesis, the method including: decellularizing the tissue; subjecting the decellularized tissue to a cross-linking solution including glutaraldehyde; subjecting the tissue to a shape- and structure-stabilizing step, in which the tissue is exposed to a first solution containing glycerol and is exposed to a second solution containing polyethylene glycol; and drying the tissue after the shape- and structure-stabilizing step.

Method for reducing paravalvular leaks with decellularized tissue

A method of preparing biological tissue for use as a component of an implant, in particular as part of a vascular implant, more particularly as part of a heart valve prosthesis, which can be implanted by a catheter. The biological tissue is decellularized using a detergent, which includes surfactin and deoxycholic acid (DCA).

Method for the preparation of biological tissue for dry use in an implant

Growing community of inventors

Fuerth, Germany

Nina Foh