Alexion Pharmaceuticals, Inc.

Mythic Therapeutics, Inc.

Nimish Gera

Paul P Tamburini

Douglas L Sheridan

Julian Chandler

Siddharth Jindal

Bridget Puffer

Brian P Fiske

Alexander J Nichols

Provided herein are antibodies and uses of the same.

Anti-cMet antibody-drug conjugates and uses thereof

The disclosure provides engineered polypeptides that specifically bind to human complement component C5 and/or serum albumin. The disclosure also provides fusion proteins comprising such engineered polypeptides, wherein such fusion proteins may be multivalent and multi-specific fusion proteins. The disclosure further provides nucleic acid molecules that encode such engineered polypeptides or fusion proteins, and methods of making such engineered polypeptides or fusion proteins. The disclosure further provides pharmaceutical compositions that comprise such engineered polypeptides or fusion proteins, and methods of treatment using such engineered polypeptides or fusion proteins.

Polypeptides that bind complement component C5 or serum albumin and fusion proteins thereof

Growing community of inventors

Waltham, MA, United States of America

Nimish Gera