Bausch-lomb Incorporated

Nimai C De

David J Heiler

Suzanne F Groemminger

Anil M Salpekar

David A Marsh

Wanda G Richard

Irene Moran

Yeshwant Sanzgiri

The present invention is directed to a lubricant for contact lenses or dry eye or to provide relief from eye irritation. In particular, the composition contains a biguanide preservative in combination with polyvinylpyrollidone. An ophthalmic solution containing such a combination of components can be applied, in the form of droplets, to the eye or to contact lens in the eye. In one embodiment of the invention, the composition is used as a universal lubricant, meaning that the same solution can be used with or without contact lenses, depending on the needs of the user, whether in the context of a contact-lens care or general eye care.

Method and composition for rewetting contact lenses and relieving eye dryness

This invention relates to the treatment of pool surfaces and equipment with antimicrobial solutions which contain straight chain alkylamine compounds alone or in combination with additional bactericidal agents, such as biguanides.

Swimming pool treatment

A composition for delaying release of an active component into an aqueous fluid is taught which includes a capsule that swells in the presence of an aqueous fluid allowing moisture to enter the capsule into contact with a capsule decomposing agent activated by the entering moisture such that the agent decomposes the capsule sufficiently to release the active agent at a predetermined delayed time after the capsule contacts the aqueous fluid. A preferred capsule composition is gelatin and decomposing agents are a proteolytic enzyme or a salt that effects the osmotic gradient of the system. The controlled release composition of the invention is preferably utilized in a soft contact lens disinfecting system wherein a solution of hydrogen peroxide disinfects the lenses followed by neutralization of residual hydrogen peroxide wherein release of the neutralizing agent is delayed by means of the capsule proteolytic enzyme or salt composition.

Controlled release composition for active substances into an aqueous

Contact lenses are cleaned by contacting the lenses with a composition containing an effective amount of one or more cyclodextrins. The compositions can also be employed at elevated temperatures or may contain suitable antimicrobial agents in order to simultaneously clean and disinfect the lenses.

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Rochester, NY, United States of America

Nimai C De