University of Florida Research Foundation Inc

Blackbox, Inc.

Nikolaus Gravenstein

Samsun Lampotang

David Erik Lizdas

Dietrich Gravenstein

Richard Joel Melker

Donn Dennis

Wilhelm K Schwab

Christopher D Batich

Francesca K Enneking

Michael Joseph Banner

Joachim S Gravenstein

Dinesh Ochhavlal Shah

Timothy E Morey

Gordon L Gibby

Yashwant Singh Bisht

Jerome H Modell

Isaac Thomas Luria

Anwer Sultan

Mark J Rice

Charles T Klodell

John Joseph Tumino

Dasia Esener

Michael D Gilmore

J E Beneken

Matthew James Peterson

Michael A Brooks

Robert J Atwater

Daraius Hathiram

Lori Deitte

Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets in a tube, drainage tube or assembly. In one such embodiment, gas pockets are vented to inhibit excessive back-pressure or suction on an organ, vessel or cavity being drained. In another such embodiment, loops in the tubes are avoided by using a mechanical template in the form of a groove or peg assembly to thread the slack in the drainage tube to generate a monotonic gradient. In another embodiment, such as for active drainage systems, a bypass channel is provided that allows an applied vacuum to go around an obstruction created by the collection of fluid in an undrained dependent loop.

Context-sensitive flow interrupter and drainage outflow optimization system

Methods and systems for patient participatory care and monitoring are provided for applications including respiratory care, ECG monitoring, capnography, infusion pump alarm prevention/management, pressure sore prevention, incentive spirometry, consciousness monitoring during sedation, pain management and other care and monitoring modalities. A patient in-the-loop system includes an input interface for receiving data acquired from a monitoring, controlling or sensing device, a storage device for storing the data at a first location, and a processor for analyzing artifacts in the data and determining whether the patient provided a deliberate action with respect to the device as a response to a prompt or query. The processor can further initiate a variety of prompts and/or output queries stored in the storage device at a second location to the patient. The data derived from these patient-in-the-loop techniques are formatted to be received and interpreted by electronic medical record and electronic record keeping systems.

Patient in-the-loop participatory care and monitoring

An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.

Interactive mixed reality system and uses thereof

Embodiments of the present invention are related to apparatus and methods for acoustically monitoring the performance of a medical device disposed within the body of a patient. According to one embodiment of an apparatus, the apparatus includes at least one acoustic sensor and a computer system that is connected to receive information from the acoustic sensor, wherein the acoustic sensor is adapted to receive a set of acoustic information that corresponds to acoustic activity within the body of said patient. The computer system is adapted for: (A) receiving the set of acoustic information, and (B) using the set of acoustic information to calculate location information relating to a location of a source of the acoustic activity.

Acoustic system for monitoring the performance of left ventricle assist devices and other mechanical devices implanted in a patient's body

Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

Methods and devices for noninvasive measurement of energy absorbers in blood

The subject invention provides a panoramic, interactive, seamless, intuitive, high-resolution and yet extensive simulation tool capable of simulating dynamic events that alter the panoramic view in response to the user's actions or inaction. The dynamic panorama simulation can generate and display novel scenes that are not limited to static 'canned' content that has been previously photographed, rendered, recorded, captured or filmed thus providing great flexibility, contextual authenticity and liveliness and, in some instances, unanticipated and surprising but accurate developments in the simulation.

Display-based interactive simulation with dynamic panorama

The subject invention provides materials and methods for convective and/or conductive and/or evaporative cooling of individuals, such as athletes and contestants, for safety, comfort, and enhanced performance. The materials and methods of the subject invention can, advantageously, be used to modify body core temperature or rate of change of temperature. Other uses include heating players or player parts (e.g., a kicker's leg, a pitcher's arm) in cold weather conditions.

Materials and methods for maintaining proper body temperature

Systems and methods are provided for monitoring use of handwashing agents to determine compliance with hand hygiene guidelines. A handwashing agent is provided with a detectable, volatile compound, such as odors, which is then rubbed onto a subject's hands using the subject's handwashing technique. After the handwashing event, the subject's hand is then exposed to an detector (such as a badge), which includes a sensor capable of detecting the volatile compound, and an indicator that communicates detection of the volatile compound, indicating use of the handwashing agent and hand hygiene compliance.

Handwashing compliance detection system

Systems and methods are provided for monitoring use of hand washing agents to determine compliance with hand hygiene guidelines. A hand washing agent is provided with a detectable, volatile compound, such as odors, which is then rubbed onto a subject's hands using the subject's hand washing technique. After the hand washing event, the subject's hand is then exposed to an detector (such as a badge), which includes a sensor capable of detecting the volatile compound, and an indicator that communicates detection of the volatile compound, indicating use of the hand washing agent and hand hygiene compliance.

Hand washing compliance detection system

A microemulsion delivery system for water insoluble or sparingly water soluble drugs that comprises a long polymer chain surfactant component and a short fatty acid surfactant component, with the amount of each being selected to provide stable microemulsion or micellar systems.

Microemulsion and micelle systems for solubilizing drugs

Growing community of inventors

Gainesville, FL, United States of America

Nikolaus Gravenstein