Synovo Gmbh

Nikolas Pietrzik

Christiane Baeuerlein

Jan Hinrich Guse

Kornelia Eitel

Martin Reisser

Michael W Burnet

Jan-Hinrich Guse

Mary Eggers

Ulrike Hahn

Simon Strass

The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Detecting microbial infection in wounds

Construct including an anchor, an enzyme recognition site and an indicator region for detecting microbial infection in wounds

Lysosomally accumulated substances that release a nitroxy group, or a short chain fatty acid or a product of anaerobic metabolism or a thiol or a sulfide often from an ester or similar labile linkage have anti-inflammatory, anti-cancer and anti-bacterial activity. They are useful in treating infectious, inflammatory and malignant disease.

Anti-infective and anti-inflammatory compounds

Growing community of inventors

Tübingen, Germany

Nikolas Pietrzik