The Medical College of Wisconsin, Inc.

Nikolai Mickevicius

Eric S Paulson

Simultaneous multi-orientation ('SMO') magnetic resonance imaging (“MRI”), in which arbitrarily-oriented slices are simultaneously imaged, is described. The SMO techniques can include any number of pulse sequences that are adapted to acquire data from two or more arbitrarily oriented slices. In general, an SMO acquisition includes sequentially exciting two or more arbitrarily rotated slices that share a common spatial encoding axis (e.g., a common frequency encoding direction) and simultaneously acquiring data from the excited slices.

Simultaneous multi-orientation magnetic resonance imaging

Systems and methods for providing image guidance for motion tracking and compensation in magnetic resonance imaging ('MRI') guided therapies, such as MRI-guided radiation therapies using an MR-linac or other MRI-guided radiation therapy system, are described. Simultaneous orthogonal plane imaging (“SOPI”) is used to acquire images from a first slice that remains static throughout the acquisition, and from a plurality of slices that are orthogonal to the first slice. This first slice can be referred to in some instances as a “tracking” or “navigator” slice, and the plurality of slices that are orthogonal to the first slice can be referred to as “imaging” slices. The tracking slice images can be used to estimate motion of the subject that occurred during the data acquisition, and to track the position of targets (e.g., anatomical targets) during the delivery of radiation treatment.

Method for real-time motion monitoring and dose accumulation in magnetic resonance guided therapies using simultaneous orthogonal plane imaging

Described here are systems and methods for providing three-dimensional motion estimates prior to and during MRI-guided therapies. In general, these systems and methods can include simultaneous orthogonal plane imaging ('SOPI'), synthetic volumetric imaging ('SVI'), self-navigated phase-resolved 4D MRI, radial CAIPIRINHA, and combinations thereof.

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Milwaukee, WI, United States of America

Nikolai Mickevicius