Johnson & Johnson Consumer Companies, Inc.

The General Hospital Corporation

Johnson & Johnson Consumer Inc.

Lifescan Corporation

Instruments S.a.

Masimo Laboratories, Inc.

J&j Consumer Companies, Inc.

Argose, Inc.

Johnson & Johnson Consumer Products, Inc.

Nikiforos Kollias

Gregory Payonk

Jeffrey Pote

Kenneth Merola

Jenny E Freeman

Wei Dong Tian

Thomas J Flotte

Georgios Stamatas

R Rox Anderson

Ying Sun

Jeffrey Adam Bloom

Michael J Hopmeier

Apostolos G Doukas

Derek Brand

Pierre C Trepagnier

James Mansfield

Benjamin C Wiegand

Daniel J McAuliffe

Steven A Shaya

John Anthony Singarayar

Robert Gillies

Georgios N Stamatas

Jeffrey M Wu

Jue-Chen Liu

Katharine Martin

Janeta Nikolovski

Ellen S Kurtz

Shun Lee

Dick Jackson

Neal Matheson

Laura McCulloch

Neena Tierney

Eduardo Ruvolo

Anthony F Coston

Gabriela Oana Cula

Kathryn Dean

Ray Kaminski

Luciann Hruza

Arthur Pellegrino

Jessica L Fewkes

Jerome D Fallon

Florence Natter

Jeffrey S Pote

Georgias Stamatas

Kelly Huang

Kenneth Pote

The present invention relates to a method of determining skin health of an area of skin by exposing the area of skin to a first exposure radiation to induce the area of skin to emit a first fluorescent emission, measuring the intensity of the first fluorescent emission, exposing the area of skin to a second exposure radiation to induce the area of skin to emit a second fluorescent emission, measuring the intensity of the second fluorescent emission, calculating a ratio of these intensities, and comparing the ratio to a control ratio.

Method of assessing skin

A method for demonstrating pre-emergent pimples is disclosed. The method includes providing a camera having a 25 mm macro lens and a linear polarizing filter including from 10 to 50 narrow band filters in the spectral range of 400-970 nm, and a light source having a linear polarizer oriented vertical to a polarization plane of the camera polarizer; taking a sequence of images of the face of a subject with the camera; creating an erythema map of the imaged area using oxy-hemoglobin values at each corresponding pixel; taking a visible-light image of the face of the subject; and comparing the images to see pre-emergent pimples. The method enables consumers to see pre-emergent pimples and treat them, which results in preventing the pimples from emerging or reducing the emergence of the pimples.

Method for demonstrating pre-emergent pimples

Systems and methods of utilizing communications networks and multivariate analysis to predict or recommend optimal products from a predefined population of commercially available products are disclosed. The recommendations are based on intelligence contained in processing elements and subjective and/or objective product information received from consumers or input to the systems as part of their initial setup. The output of the systems comprise sets of products that they predict the consumer will prefer and/or perform well for the problem or concern identified by the consumer. The performance and preference predictions are a function of consumer problems and product responsiveness patterns. Objective product information is generally obtained with diagnostic instruments. Data measured with the diagnostic instruments may be communicated to the data processing portions of the invention via the Internet. The outputs of the data processing portion of the system may be presented to consumers via the Internet as well.

Intelligent performance-based product recommendation system

The present invention relates to a method of determining skin health of an area of skin and overall health of an individual by exposing the area of skin to a first exposure radiation to induce the area of skin to emit a first fluorescent emission, measuring the intensity of the first fluorescent emission, exposing the area of skin to a second exposure radiation to induce the area of skin to emit a second fluorescent emission, measuring the intensity of the second fluorescent emission, calculating a ratio of these intensities, and comparing the ratio to a control ratio.

Method of assessing skin and overall health of an individual

A standard used to test imaging systems is imaged by a digital camera which expresses the image of the standard as a plurality of pixels having associated intensities. A computer automatically finds the image of the standard in the image and quantitatively compares intensities of pixels of a subsequent image of the standard to the first image to discern changes indicative of malfunction. A set of images of the standard may be collected and compiled to develop standard data, such as average of median values, that can be used to test imaging apparatus. The standard may be provided with a plurality of types of imaging standards occupying sub-areas that produce a different photoresponse to a plurality of different light sources. A fluorescent standard may be included that has a plurality of different fluorescence levels. Multiple sub-areas of the same type may be distributed over the surface area of the standard to measure the photoresponse in several areas and also to facilitate locating all sub-areas of the standard, e.g., multiple white squares may be distributed over the standard that may be identified by thresholding. The results of testing via the standard may be graphically displayed.

Imaging standard apparatus and method

A fluorescence standard for identifying variations in illumination during imaging has a composite fluorescent laminar structure, which fluoresces in response to light in the approximate wavelength range of 375 nm to 430 nm. The fluorescent object has at least two areas with different fluorescent response, e.g., a first made from a strongly luminescing material, such as GG420 filter glass. A portion of the GG420 glass is covered by filter glass having an attenuating effect on the fluorescent response. In accordance with a method of the present invention, variations in illumination during imaging with a camera are detected by placing the standard before the camera during imaging. Each captured image may contain the image of the standard and the fluorescent response of the standard in different images can be compared to identify any response changes due to variations in illumination. The variations in illumination can then be remediated by adjusting the source of illumination, the camera or ambient lighting. Alternatively, the images can be normalized through digital image processing.

Calibration apparatus and method for fluorescent imaging

A skin testing and imaging station and corresponding method for capturing, displaying and analyzing images of a person and for testing the skin using a variety of probes includes a digital camera, a light source capable of providing at least two different wavelengths of light, a plurality of probes for conducting skin tests, a touch-screen display and a computer for controlling the components of the station. The apparatus selectively captures and displays a plurality of digital images using different wavelengths of illuminating light, e.g., using a plurality of flashes and filters, some of which may be adjustable to adjust the angle of incidence of the illuminating light on the subject. In video mode, the camera displays a real time image on the display facilitating a user to position a probe for testing any specific area of the skin. Preferably, the apparatus is self-serve, allowing any person to capture, review and analyze the images and skin data. Verbal and/or graphic instructions to a user aid in use of the station. An intuitive graphic user interface with thumbnail images is employed. Focus control, zoom and synchronized side-by side comparison of images are available.

Skin imaging system with probe

Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

Non-invasive tissue glucose level monitoring

An imaging station for taking a plurality of digital images of a subject under a plurality of illuminating conditions and storing and analyzing the digital images, includes a housing, containing the digital image capturing apparatus, like a camera or video recorder, a computer for processing the image data and one or more displays for displaying images of the person. The imaging station aids in controlling lighting during image capture and may be used to optimally position the subject for imaging. The computer may be programmed to conduct various image processing functions and may be networked to allow image sharing. A display which may be provided on the exterior of the housing allows an operator to visualize the subject and to control the imaging process. The imaging station may be used for teaching purposes.

Imaging apparatus and methods for capturing and analyzing digital images of the skin

A self-contained, portable apparatus and corresponding method for capturing, displaying and analyzing images of a person includes a housing for containing a digital camera, a light source capable of providing at least two different wavelengths of light, a touch-screen display and a computer for controlling the camera, the light source and the display. The apparatus selectively captures and displays a plurality of digital images using different wavelengths of illuminating light. The light source may include a plurality of flashes and filters, some of which may be adjustable to adjust the angle of incidence of the illuminating light on the subject. Preferably, the apparatus is self-serve, allowing any person to capture, review and analyze the images. To that end, the apparatus may provide a moving image and verbal instructions to a user to aid in positioning themselves relative to the camera. Instruction may further be provided by text or internet connection for using the apparatus and/or interpreting the captured images. An intuitive graphic user interface with thumbnail images is employed. Focus control, zoom and synchronized side-by side comparison of images are available.

Apparatus for and method of taking and viewing images of the skin

An apparatus and method for assessing photodamage has a digital imaging system for recording blue light imagining and in particular the green signal response intensity of the skin of a person, which is indicative of elastotic material and photodamage. Because the image data has a numerical intensity value, which may be expressed in RGB or L*a*b* colorspace, the image data taken from one image can be numerically compared to that of one or more other images and the image data is amenable to numerical and statistical analysis. Comparison to population profiles/image data permits an individual's image data to be characterized numerically, such as by a relative score or percentile rating. The image data can also be used to ascertain the degree of variation over a surface such as the face, with wider variation being indicative of greater photodamage.

Apparatus and method for measuring photodamage to skin

The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; a first light emitting diode; and a carrier containing an active agent; wherein the power source is in electric communication with the first conductive electrode, the second conductive electrode, and the light emitting diode, and wherein the device is arranged such that light from the first light emitting diode and the carrier are in communication with the barrier membrane contacting surface.

Device containing a light emitting diode for treatment of barrier membranes

The present invention relates to a method and a device for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of: ablating said membrane with a shear device; and utilizing a driving force to move said molecule through said perforated membrane.

Tissue ablation by shear force for sampling biological fluids and delivering active agents

The present invention relates to a method of assessing the efficacy of skin care products by comparing images of the skin prior to and after use of said skin care product.

Method of promoting skin care products

Growing community of inventors

Skillman, NJ, United States of America

Nikiforos Kollias