Massachusetts Institute of Technology

Nikhil Padhye

Bernhardt Levy Trout

David Moore Parks

Alexander H Slocum, Jr

Won Sik Kim

Trevor Alan Hatton

Allan Stuart Myerson

Gregory C Rutledge

Yi Du

Jung-Hoon Chun

Salvatore Mascia

Keith M Forward

Emily Chang

Himanshu Hemant Dhamankar

James M B Evans

Ryan Richard Slaughter

Mao Wang

Blair Kathryn Brettmann

James Mb Evans

Methods and apparatuses for bonding polymeric parts are disclosed. Specifically, in one embodiment, the polymeric parts are bonded by plastically deforming them against each other while they are below the glass transition temperatures.

Plasticity induced bonding

Methods and apparatuses for bonding polymeric parts are disclosed. Specifically, in one embodiment, the polymeric parts are bonded by plastically deforming them against each other while they are below the glass transition temperatures. A method includes: placing a first polymeric part in contact with a second polymeric part; and plastically deforming the first polymeric part and the second polymeric part against each other to bond the first polymeric part to the second polymeric part. Additionally, during the plastic deformation, a temperature of the first polymeric part is less than a glass transition temperature of the first polymeric part and a temperature of the second polymeric part is less than a glass transition temperature of the second polymeric part.

T-peel test fixture for a vertical test machine. The test fixture includes an upper grip for holding an arm of a peel specimen that has a hangover tail and a lower grip for holding the other arm of the peel specimen. A first rack is connected to a support hanger. The upper grip and the first rack move in a vertical direction at a selected speed. A second rack including a support plate located to support the specimen hangover tail is driven in the vertical direction at one-half the selected speed. The fixture thus supports the hangover tail so that symmetry is maintained with respect to gravity to suppress the interfering effect of gravity on a peel test.

T-peel test fixture

Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.

Layer processing for pharmaceuticals

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Sunnyvale, CA, United States of America

Nikhil Padhye