Koninklijke Philips Corporation N.v.

Tpo Hong Kong Holding Limited

Koninklijke Electronics N.v.

Philips Intellectual Property & Standards Gmbh

Nijs Cornelis Van Der Vaart

Bernardus Hendrikus Wilhelmus Hendriks

Jan Frederik Suijver

Jurgen J L Hoppenbrouwers

David Andrew Fish

Szabolcs Deladi

Roel Van Woudenberg

Ladislav Jankovic

Yan Shi

Erik A Harks

Stein Kuiper

Alan G Knapp

Herbert Lifka

Michael Harald Kuhn

Maya Ella Barley

Thomas Zaengel

Franciscus P M Budzelaar

Wouter Harry Rensen

Hans-Helmut Bechtel

Siebe Tjerk De Zwart

Mark Johnathan Childs

Nigel David Young

Gerhardus Wilhelmus Lucassen

Christopher Stephen Hall

Theunis S Baller

Klaas Cornelis Jan Wijbrans

Martin Gerard Hendrik Hiddink

Antonius Hendricus Maria Holtslag

Wouter Harry Jacinth Rensen

Georg Friedrich Gaertner

Gerhard Spekowius

Marc Wilhelmus Gijsbert Ponjee

Cornelis Adrianus Henricus Antonius Mutsaers

Petrus Hubertus Franciscus Trompenaars

Anna Teresa Fernandez

Gerardus G P Van Gorkom

Jarich Willem Spliethoff

Gerardus Gegorius Petrus Van Gorkom

Petrus H F Trompenaars

Maya E Barley

Erik Robbert Vossenaar

Eduard M J Niessen

Ronald Tabaksblat

Yan S Shi

Wouter H J Rensen

Erik Robert Vossenaar

A system SY for determining a tissue type TY of a tissue region TR is provided in which the distal ends OFDEof at least three optical fibers define a plurality of intersecting optical paths IOPwithin the tissue region TR. A tissue signal Qindicative of a tissue type TY for the respective optical path IOPis generated from said spectral measurement data SMD corresponding to each of the plurality of intersecting optical paths IOP. Each tissue signal Qis compared with a reference threshold QRT for the tissue type, and with an average of the tissue signals QMA. At least a portion of the tissue region is identified as the tissue type TY if i) every tissue signal Qin the tissue region TR indicates that its corresponding tissue is not the tissue type TY in the comparison with the reference threshold QRT and ii) at least one of the tissue signals Qin the tissue region TR lies between the average QMA of the tissue signals Qand the reference threshold QRT, and a difference Δ between the at least one tissue signal Qand the average QMA of the tissue signals Qexceeds a predetermined value ΔP.

Tumor margin assessment

The present invention relates to a monitoring apparatus for monitoring an ablation procedure. The monitoring apparatus comprises an ultrasound signal providing unit for providing an ultrasound signal that depends on received echo series of an object that is ablated. The monitoring apparatus further comprises an ablation depth determination unit for determining an ablation depth from the provided ultrasound signal. The ablation depth can be determined directly from the ultrasound signal and is an important parameter while performing an ablation procedure. For example, it can be used for determining the progress of ablation within the object and for determining when the ablation has reached a desired progression.

Monitoring apparatus for monitoring an ablation procedure

The present invention relates to a monitoring apparatus () for monitoring an ablation procedure. The monitoring apparatus () comprises an ultrasound signal providing unit for providing an ultrasound signal that depends on received echo series of an object () that is ablated. The monitoring apparatus () further comprises an ablation depth determination unit () for determining an ablation depth from the provided ultrasound signal. The ablation depth can be determined directly from the ultrasound signal and is an important parameter while performing an ablation procedure. For example, it can be used for determining the progress of ablation within the object () and for determining when the ablation has reached a desired progression.

The invention relates to a method of determining in vitro the amount of nuclear DNA within a human or animal cell using UV absorption measurement with UV light. The invention also relates to a method for detecting in vitro cancerous cells in a biological sample relying on the aforementioned principles. The invention also relates to an in vitro method of diagnosing or predicting the likely occurrence of cancer in a human or animal subject.

Vitro method of detecting and/or diagnosing cancer using UV light based DNA image cytometry

The invention relates to an ingestible capsule and method for in vivo imaging and/or treatment of one or more diseased areas of interest within the gastrointestinal tract of an animal or human being. The capsule comprises an image sensor; a lens system for focusing images onto the image sensor; at least one light source for illumination of the tissue area of interest, the at least one light source optionally being capable of providing optical therapeutic treatment to the diseased areas; a variable lens system located in front of the at least one light source, wherein the variable lens system comprises beam steering means and focusing means for directing and focusing the light beams from the at least one light source onto the diseased tissue areas; a control unit in communication with the image sensor, the at least one light source, and variable lens system, the control unit comprising image storing means, processing means and image transmission means; wherein the control unit correlates stored images received from the image sensor as the capsule travels through the gastrointestinal tract and controls the beam steering means and focusing means of the variable lens system to ensure that the light beams from the at least one light source are directed and focused onto the diseased tissue areas; a power source for powering the image sensor, the at least one light source and the control unit; and a non-digestible, transparent outer protective shell configured to pass through the gastrointestinal tract, housing within the image sensor, the lens system, the at least one light source, the variable lens system, the control unit and the power source.

Capsule camera with variable illumination of the surrounding tissue

The application relates to an ingestible capsule and method for in vivo imaging and/or treatment of one or more diseased areas of interest within the gastrointestinal tract of an animal or human being. The capsule comprises an image sensor; a lens system for focusing images onto the image sensor; at least one light source for illumination of the tissue area of interest, the at least one light source optionally being capable of providing optical therapeutic treatment to the diseased areas; a variable lens system located in front of the at least one light source, wherein the variable lens system comprises beam steering means and focusing means for directing and focusing the light beams from the at least one light source onto the diseased tissue areas, &#x2014;a control unit in communication with the image sensor, the at least one light source, and variable lens system, a power source for powering the image sensor, the at least one light source and the control unit; and a non-digestible, transparent outer protective shell configured to pass through the gastrointestinal tract, housing within the image sensor, the lens system, the at least one light source, the variable lens system, the control unit and the power source.

A catheter apparatus includes an elongated body having proximal and distal ends, and an acoustic transducer disposed proximate the distal end of the elongated body. A variably-refracting acoustic lens is provided to dynamically adjust a direction associated with an acoustic wave coupled to the acoustic transducer in response to one or more control signals provided thereto.

Catheter for three-dimensional intracardiac echocardiography and system including the same

In an active matrix electroluminescent display device, comprising an array of display pixels, each pixel comprises an electroluminescent display element, active matrix circuitry including at least one drive transistor for driving a current through the display element, means for determining an overall brightness level of an image to be displayed in a frame period, means for controlling the at least one drive transistor of each pixel in dependence on, (1) a respective input signal providing a drive level for the pixel, and (2) the overall brightness level. The novel arrangement is capable of controlling the pixels to limit the maximum currents drawn by the pixels, thereby limiting cross-talk effects resulting from voltage drops along row or column conductors. If an image is bright, the pixel drive levels across the image, or at least part of the image, can be reduced, so that the maximum brightness is reduced.

System and method for determining an overall brightness level of an image to be displayed in a frame period in electroluminescent display devices

In an active matrix electroluminescent display, a plurality of rows of pixels are illuminated, defining at least two bands of rows separated by a non-illuminated band. The bands of rows of pixels scroll in the column direction over time, and at most 75% of the rows are illuminated at any point in time. This method is in essence a double bar scrolling method. By scrolling two bars, the required peak brightness is reduced as the effective overall duty cycle is increased. However, the period of illumination can still remain short, so that motion perception remains improved. The scrolling speed can be halved for the same frame rate or else the frame rate can be increased to reduce flicker.

Electroluminescent display devices

A display panel includes pixels with a light emissive layer and an electrode layer deposited on the light emissive layer. A first pixel is determined by a first barrier structure and a second pixel, adjacent to the first pixel, is determined by a second barrier structure. The first and second barrier structures are separated by an electrically conductive structure in electrical contact with the electrode layer. Accordingly, space is available between the barrier structures for electrical shunting of the electrode layer.

Display panel and method for manufacturing the same

In an active matrix electroluminescent display device, an overall brightness level of an image to be displayed in a frame period is determined. A drive transistor of each pixel is controlled in dependence on an input drive signal for the pixel and on the overall brightness level, for example using a signal processor () to vary the pixel drive signals. This arrangement can control the pixels to limit the maximum currents drawn by the pixels, thereby limiting the cross talk effects resulting from voltage drops along row or column conductors. If an image is bright, the pixel drive levels across the image (or at least a part of the image) can be reduced, so that the maximum brightness is reduced.

Control of current supplied by a transistor to a pixel in an electroluminescent display device

A color electroluminescent, EL, display device comprising an array of pixels () each comprising sub-pixels () of two or more colors (R, G, B). For at least one of the colors (R, G, B), the pixel () comprises a first sub-pixel (R, G, B) comprising a first EL material and a second sub-pixel (R, G, B) comprising a second EL material. The first EL material is of higher lifetime than the second EL material; the second EL material has better color points and/or better color rendition properties than the first EL material. In some embodiments a pixel comprises two red sub-pixels (R, R), two green subpixels (G, G) and two blue sub-pixels (BL, Bc), one sub-pixel of each color (R, G, B) comprising relatively high lifetime EL material and the other sub pixel of each color (R, G, B) comprising relatively good color points EL material. In other embodiments a pixel comprises two blue sub-pixels (B, B) but only one red sub-pixel and one green sub-pixel.

Colour electroluminescent display device and its driving method

A display panel is formed on a substrate and includes display pixels with at least one light emissive layer and at least one electrode layer or cathode deposited on or over said light emissive layer. The display panel further includes electrically conductive structures shunting the electrode layer. The barrier structures separating the display pixels may be used as the electrically conductive structures.

Display panel comprising conductive barrier structures

The invention relates to a vacuum display device comprising a display screen () having picture elements (), cathode means () for generating a plurality of electron beams (EB), each corresponding to one of the picture elements (), and addressing means () for addressing the picture element () through modulation of the intensity of an electron beam corresponding to the picture element (). A channel structure () is arranged adjacent the cathode means (). The channel structure () comprises a plurality of electron beam guidance cavities (), each corresponding to one of the picture elements (), and protects the cathode means () from incident ions. The exit () of the cavity () is smaller than the entrance (), so that an electron beam (EB) exiting from the cavity () has a particularly high brightness and spatial uniformity.

Vacuum display device

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Rosmalen, Netherlands

Nijs Cornelis Van Der Vaart