Glaxo Group Limited

Mini-mitter Company, Inc.

Nigel Robert Oakley

Alexander W Oxford

Ian H Coates

Peter C North

Dennis M Ebner

Gary Steven Ungless

Clive A Halliday

Score values representing a user's subjective rating of a condition as recorded using a monitor worn by or secured to the user. The monitor includes a clock for generating a periodic timing signal, a user interface for entering score values and a transducer for prompting the user to enter a score value. A time storage device stores timing information and a data storage device for stores time values and related score values. A controller activates the transducer at times indicated by the timing information. The stored time values and related score values can be read from the data storage device.

Monitor for input of subjective rating scores

The invention relates to the use of a compound which acts as an antagonist of 5-HT at 5-HT.sub.3 receptors in the treatment of autism or another disorder originating in childhood in which there is mental retardation.

5-HT.sub.3 receptor antagonists for the treatment of autism

The use of the compound of formula (II) or a physiologically acceptable salt or hydrate thereof in the treatment, relief or prevention of the effects of anxiety ##STR1## The compound of formula (II) is described in UK Published Patent Application No. 2157691A. The preferred compound for use in this indication is (.+-.)-trans-5-fluoro-2,3,3a,9a-tetrahydro-1H-[1,4]-benzodioxino[2,3-c]-py rrole, especially in the form of its hydrochloride salt.

Medicaments

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Cambridge, United Kingdom

Nigel Robert Oakley