Oneness Biotech Co.

Academia Sinica

Fountain Biopharma Inc.

Nien-Yi Chen

Kung-Ming Lu

Hung-Chi Chen

Tien-Tien Cheng

Winston Town

Che-Haorz Wu

Chien-Jen Lin

Jiun-Bo Chen

Tse Wen Chang

Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the Cεmx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.

Treating IgE-mediated allergic diseases

Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C&#x3b5;mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.

Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.

Methods for producing recombinant glycoproteins with modified glycosylation

Antibodies binding to junction regions between the CH4 and C&#x3b5;mX domains of membrane-bound IgE and uses thereof in treating IgE-mediated diseases such as allergic diseases.

Growing community of inventors

Taipei, Taiwan

Nien-Yi Chen