Qiagen Gmbh

Exiqon A/s

Niels Tolstrup

Søren Morgenthaler Echwald

Sakari Kauppinen

Niels B Ramsing

Peter Mouritzen

Peter Stein Nielsen

Søren Mørk

Peter Arctander

Niels Tommerup

Carsten Alsbo

Henrik Vissing

Daniel C Jeffares

Tobias Mourier

Soren Morgenthaler Echwald

Sören Morgenthaler Echwald

The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantitating components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.

Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same

The invention features improved nucleic acids and methods for expression profiling of mRNAs, identifying and profiling of particular mRNA splice variants, and detecting mutations, deletions, or duplications of particular exons or other splice variants, e.g., alterations associated with a disease such as cancer, in a nucleic acid sample, e.g., a biological sample or a patient sample.

Oligonucleotides useful for detecting and analyzing nucleic acids of interest

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Klampenborg, Denmark

Niels Tolstrup