Ecole Polytechnique Federale De Lausanne

Diagnoswiss S.a.

Niels Lion

Hubert Hugues Girault

Frédéric Reymond

Joel Stephane Rossier

Christophe Roussel

Baohong Liu

Tatiana Rohner

Qiao Liang

Véronique Gobry

Pengyuan Yang

A plate for matrix-assisted laser desorption ionization (MALDI) mass spectrometry comprising an electrically conductive substrate () covered with a light sensitive matrix (), the matrix () comprising a light absorber, a charge carrier, a probe molecule and a photo-sensitizer () arranged to oxidize the probe molecule when irradiated with light ().

Ionization device

The present invention relates to an apparatus and a method of fabricating the apparatus for dispensing a sample for subsequent analysis by mass spectrometry. The apparatus comprises a polymer substrate (), in which a covered microchannel () has been etched, a wall of the microchannel comprising an electrically conductive material () for applying a voltage allowing the sample to be sprayed into a mass spectrometer from the open end () of the microchannel. The present application also discloses various applications of the apparatus.

Apparatus and method for dispensing a sample

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Lausanne, Switzerland

Niels Lion