Dabur Pharma Limited

Nidhi Rani

Rama Mukherjee

Anand C Burman

Manu Jaggi

Anu T Singh

Anand Vardhan

Manoj Kumar Singh

Praveen Rajendran

Vivek Kumar

Mohammad Jamshed Ahmed Siddiqui

Shiv Kumar Agarwal

Hemant Kumar Jajoo

Sanjay Kumar Srivastava

The invention relates to novel betulinic acid derivatives of formula (I), wherein R is C(&#x2550;CH)CHor CH(CH); Rtogether with the adjacent carbonyl group forms a carboxylic acid, carboxylic acid ester or amide or substituted amide; Ror Rare hydrogen or aryl with the proviso that both are not independently hydrogen or alkyl or Rand Rare combined together to form an aryl ring optionally substituted with a group X, wherein X is selected from halogen, alkyl, cyano, nitro, alkoxy, amino or substituted amine; Y is N or O; and Ris zero when Y is O, and Ris hydrogen, alkyl or aryl alkyl when Y is N, useful for inhibition of tumor cancer cells. 

Betulinic acid derivatives

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Uttar Pradesh, India

Nidhi Rani