The General Hospital Corporation

Nicole Provenza

Emad N Eskandar

Alik S Widge

Darin D Dougherty

David A Borton

In accordance with some embodiments of the disclosed subject matter, mechanisms (which can, for example, include systems, methods, and media) for detecting an effortful mental state providing real-time deep brain stimulation to enhance performance of effortful mental tasks are provided. In some embodiments, system for detecting and facilitating effortful mental states is provided, the system comprising: monitoring sensors to capture neural activity from a subject's brain; an implanted stimulator to provide electrical stimulation to the subject's brain; a hardware processor programmed to: correlate activity in a first and second region of the subject brain during task performance; correlate activity in the first and second regions during task non performance; train a support vector machine (SVM) using the correlations as first and second class examples; and provide stimulation to augment brain function when the SVM indicates, based on activity in the first and second regions, the subject is in the mental state.

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Providence, RI, United States of America

Nicole Provenza