Degussa Aktiengesellschaft

Evonik Degussa Gmbh

Degussa - Huls Ag

Other

Nicole Dusch

Georg Thierbach

Alfred Puhler

Brigitte Bathe

Mike Farwick

Mechthild Rieping

Bettina Moeckel

Christine Bastuck

Frank Elischweski

Jurgen Dohmen

Walter Pfefferle

Hermann Thomas

J&ouml;rn Kalinowski

The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family, characterized in that

Process for preparing L-amino acids using improved strains of the Enterobacteriaceae family

The invention relates to a process for the preparation of L-amino acids by the fermentation of recombinant microorganisms of the family Enterobacteriaceae. The microorganisms produce the desired L-amino acid and overexpress theoryibD gene encoding the putative glycosyl transferase enzyme. The microorganisms are cultivated in a medium under conditions in which the desired L-amino acid is enriched in the medium or in the cells. The amino acid is then isolated, optionally with constituents of the fermentation broth, and/or all or part (&#x2267;0 to 100%) of the biomass.

Process for L-amino acid production using enterobacteriaceae strains with enhanced yibD

The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family in which the ytfQ-ORF is overexpressed.

The invention relates to a process for preparing D-pantothenic acid using Coryneform bacteria in which the poxB gene is attenuated.

Process for the fermentative preparation of D-pantothenic acid using coryneform bacteria

The invention relates to a process for the preparation and improvement of D-pantothenic acid-producing microorganisms by amplification of nucleotide sequences which code for ketopantoate reductase, in particular the panE gene, individually or in combination with one another, and optionally additionally of the ilvC gene, the microorganisms containing these nucleotide sequences, and a process for the preparation of D-pantothenic acid comprising fermentation of these microorganisms, concentration of pantothenic acid in the medium or in the cells of the microorganisms, and isolation of the D-pantothenic acid.

Process for the preparation of pantothenic acid by amplification of nucleotide sequences which code for the ketopantoate reductase

The present invention relates to polynucleotides corresponding to the nadA gene and which encode the quinolinate synthetase A protein, methods of producing nicotinic acid or nicotinic acid derivatives, and methods of screening for polynucleotides which encode proteins having quinolinate synthetase A activity.

Polynucleotides encoding the nadA gene and methods of producing nicotinic acid or nicotinic acid derivatives

The present invention relates to polynucleotides corresponding to the nadC gene and which encode the nicotinate nucleotide pyrophosphorylase protein, methods of producing nicotinic acid or nicotinic acid derivatives, and methods of screening for polynucleotides which encode proteins having nicotinate nucleotide pyrophosphorylase activity.

Polynucleotides encoding the nadC gene and methods of producing nicotinic acid or nicotinic acid derivatives

The present invention provides processes for preparing D-pantothenic acid using Coryneform bacteria having an enhanced pfkA gene.

Processes for preparing D-pantothenic acid using coryneform bacteria

The invention is a method for the production of D-pantothenic acid by the fermentation of microorganisms in which at least the panD gene is enhanced (overexpressed), optionally in combination with the panB and/or panC gene, to provide for the enrichment of the pantothenic acid in the medium or the cells of the microorganisms.

Growing community of inventors

Werther, Germany

Nicole Dusch