Ludwig Institute for Cancer Research Limited

Nicolas Van Baren

Thierry R Boon-Falleur

Francis Brasseur

Pierre G Coulie

Sophie Lucas

Charles DeSmet

Methods for diagnosing multiple myeloma are disclosed. These methods are based upon the observation that tumor rejection antigen precursors are expressed in multiple myeloma. By assaying bone marrow samples, one can diagnose multiple myeloma, and also monitor the disease's progress. Therapeutic approaches to multiple myeloma are also disclosed.

Methods for diagnosing multiple myeloma by determining rejection antigen precursors

The invention describes leukemia associated genes, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a preproTRH, tryptase-L and/or Oct-T1 gene product.

Leukemia associated genes

Method for diagnosing multiple myeloma by determining tumor rejection antigen precursors

Methods for diagnosing multiple myeloma are disclosed. These methods are based upon the observation that tumor rejection antigen precursors are expressed in multiple myeloma. By assaying bone marrow samples, one can diagnose multiple myeloma, and also monitor the disease's progress. Therapeutic approaches of multiple myeloma are also disclosed.

Method for determining regression or progression of multiple myeloma

Method for determining multiple myeloma by assaying for expression of

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Brussels, Belgium

Nicolas Van Baren