Sofradim Production

Allergan Industrie, Sas

Covidien LP

Allergan, Inc.

Convidien LP

Nicolas Prost

Pierre F Lebreton

Cecile Gousse

Sebastien Francois

Sébastien Ladet

Nicholas P Maiorino

Dennis E Van Epps

Sumit Paliwal

Matthew Prescott

Thomas Corso

Michel Therin

Julie Lecuivre

Xavier Bourges

Delphine Petit

Suzelei Montanari

Sébastien Francois

The present invention relates to a synthetic prosthesis for tissue reinforcement comprising:

Synthetic prosthesis comprising a knit and a non porous film and method for forming same

The present invention relates to a surgical anti-adhesion barrier film comprising an oxidized collagen and a polyphosphate compound and to a surgical implant comprising a prosthetic fabric and such a film.

Method for preparing an anti-adhesion barrier film

Prosthesis () comprising a patch () made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided, on one () of its faces, with a single marking means () designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

Hernia prosthesis with marking means

The present invention relates to a prosthesis () for hernia repair comprising a reinforcement layer (), a first barrier layer () of anti-adhesion material covering at least a part of a surface of the reinforcement layer, and a second barrier layer of anti-adhesion material covering a remaining part of the surface of the reinforcement layer, the second barrier layer being formed of one or more flap member(s) ().

Prosthesis for hernia repair

The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a&#xb0;) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7 %, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.

Dermal filler hydrogel compositions, methods of making them, and methods of using them to treat soft tissue conditions, such as wrinkles, are provided. The compositions contain a crosslinked hyaluronic acid-based polymer and one or more additional ingredients, and are stable to sterilization by heat and/or pressure treatment. The additional ingredients include vasoconstrictive agents, antioxidant agents, such as a ascorbic acid agents, and/or anesthetic agents.

Stable hydrogel compositions including additives

The present invention relates to a process for preparing a porous layer of biocompatible polymer, having a uniform density and porosity, comprising the following steps:

Process for preparing a porous layer

The disclosure provides hyaluronic acid (HA) gel formulations and methods for treating the appearance of the skin. The formulations contain hyaluronic acid and at least one additional ingredient. Methods for treating lines, wrinkles, fibroblast depletions, and scars with the disclosed composition are provided as well.

Heat stable hyaluronic acid compositions for dermatological use

Prosthesis () comprising a patch () made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a center, a length and a width of said patch, characterized in that said patch is provided, on one () of its faces, with a single marking means () designed to indicate both the center (C) of the patch and also the longitudinal direction of said patch.

A method for manufacturing an implantable film and a prosthesis comprising such a film The present invention relates to a method for manufacturing a non porous film intended to be implanted in the human body, said method comprising the following steps: preparation of a first film, called intermediate film, via gelling of a starting solution comprising at least one polymer selected in the group consisting of collagen, glycosaminoglycans, and mixtures thereof, immersion of said intermediate film in an alkaline composition comprising at least one C-Calcohol, drying of the film obtained at the end of the immersing step. The invention also relates to a method for manufacturing a prosthesis comprising a textile support and such a film.

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Rhone, France

Nicolas Prost