Institut National De La Sante Et De La Recherche Medicale

Assistance Publique-Hopitaux De Paris

Université Paris Est Creteil Val De Marne

Etablissement Francais Du Sang

Etablissement Franais Du Sang

Renault S.a.s.

Institut National Transfusion Sanguine

Nicolas Hebert

France Noizat Pirenne

Frédéric Galacteros

Marie Georgine Rakotoson

Gaetana Vandemeulebrouck

Pablo Bartolucci

Marie Cambot

David Olivier

Pascal Herbin

The invention concerns a method for determining, by flow cytometry, the hemoglobin content of each erythroid cell of a set of erythroid cells. This method applies in particular to determining the hemoglobin content of each red blood cell of a set of red blood cells. The invention also concerns a method for determining the amount of red blood cells transfused into a patient and for monitoring the therapeutic efficacy of a treatment for sickle cell disease or β-thalassemia.

Method for determining the haemoglobin content of an erythroid cell

The invention concerns a method for determining, by flow cytometry, the hemoglobin F (HbF) content of each erythroid cell of a set of erythroid cells. This method applies in particular to determining the HbF content of each red blood cell of a set of red blood cells. The invention also concerns a method for determining the amount of red blood cells transfused into a patient and for monitoring the therapeutic efficacy of a treatment for sickle cell disease or &#x3b2;-thalassemia.

Method for determining the haemoglobin F content of an erythroid cell

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Ollainville, France

Nicolas Hebert